Oncology Service, Wills Eye Institute, Thomas Jefferson University, Philadelphia, Pennsylvania, USA.
Ophthalmology. 2011 Sep;118(9):1747-53. doi: 10.1016/j.ophtha.2011.04.034. Epub 2011 Jul 23.
To report clinical and histopathologic features of vascular tumors of the conjunctiva.
Retrospective, noninterventional case series.
A total of 140 patients.
None.
Tumor diagnosis, anatomic location, clinical features, management, and histopathology.
There were 140 vascular tumors of the conjunctiva with 93% benign and 7% malignant. The specific diagnoses included lymphangioma/lymphangiectasis (n = 54, 36%), pyogenic granuloma (n = 31, 22%), capillary hemangioma (n = 20, 14%), Kaposi's sarcoma (n = 10, 7%), acquired sessile hemangioma (n = 10, 7%), racemose hemangioma (n = 7, 5%), varix (n = 4, 3%), cavernous hemangioma (n = 3, 2%), and glomangioma (n = 1, <1%). The lesions were unilateral in 89% and discovered at median age of 41 years. Bilateral lesions included lymphangiectasia, Kaposi's sarcoma, and racemose hemangioma. All tumors were typically found in adults with the exception of capillary hemangioma (<1 year) and glomangioma (16 years). The median tumor diameter was 6 mm, with the largest median diameter (15 mm) with Kaposi's sarcoma and (12 mm) glomangioma and capillary hemangioma and the smallest median diameter (3 mm) with cavernous hemangioma. The most common anatomic sites included bulbar conjunctiva, which was extralimbal in 80 patients (57%), limbal in 19 patients (14%), tarsal conjunctiva in 27 patients (19%), and forniceal conjunctival in 24 patients (17%). Clinical features included cystic component in 24% of patients (seen with lymphangioma, glomangioma, and varix), well-defined margins in 64% of patients, and feeder vessels in 39% of patients.
A variety of vascular tumors can occur in both children and adults at various anatomic locations in the conjunctiva. They tend to occur unilaterally on the bulbar conjunctiva, and the majority of tumors are benign.
报告结膜血管肿瘤的临床和组织病理学特征。
回顾性、非干预性病例系列研究。
共有 140 名患者。
无。
肿瘤诊断、解剖位置、临床特征、治疗方法和组织病理学。
共发现 140 例结膜血管肿瘤，其中 93%为良性，7%为恶性。具体诊断包括淋巴管瘤/淋巴管扩张（54 例，36%）、化脓性肉芽肿（31 例，22%）、毛细血管血管瘤（20 例，14%）、卡波西肉瘤（10 例，7%）、获得性固定性血管瘤（10 例，7%）、蔓状血管瘤（7 例，5%）、静脉瘤（4 例，3%）、海绵状血管瘤（3 例，2%）和血管球瘤（1 例，<1%）。病变 89%为单侧，中位发病年龄为 41 岁。双侧病变包括淋巴管扩张、卡波西肉瘤和蔓状血管瘤。除毛细血管血管瘤（<1 岁）和血管球瘤（16 岁）外，所有肿瘤均发生于成年人。肿瘤最大直径中位数为 6mm，最大直径为 15mm（卡波西肉瘤）和 12mm（血管球瘤和毛细血管血管瘤），最小直径中位数为 3mm（海绵状血管瘤）。最常见的解剖部位包括球结膜，其中 80 例（57%）位于球结膜外，19 例（14%）位于角巩膜缘，27 例（19%）位于睑结膜，24 例（17%）位于穹隆结膜。临床特征包括 24%的患者有囊性成分（见于淋巴管瘤、血管球瘤和静脉瘤）、64%的患者边界清楚和 39%的患者有滋养血管。
结膜的各种血管肿瘤可发生于儿童和成人，在不同的解剖部位，多为单侧发生于球结膜，大多数为良性。
