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输尿管支架:新理念,新设计。

Ureteral stents: new ideas, new designs.

机构信息

Department of Urology, University of Patras, Greece.

出版信息

Ther Adv Urol. 2010 Apr;2(2):85-92. doi: 10.1177/1756287210370699.

DOI:10.1177/1756287210370699
PMID:21789086
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC3126070/
Abstract

Ureteral stents represent a minimally invasive alternative to preserve urinary drainage whenever ureteral patency is deteriorated or is under a significant risk to be occluded due to extrinsic or intrinsic etiologies. The ideal stent that would combine perfect long-term efficacy with no stent-related morbidity is still lacking and stent usage is associated with several adverse effects that limit its value as a tool for long-term urinary drainage. Several new ideas on stent design, composition material and stent coating currently under evaluation, foreseen to eliminate the aforementioned drawbacks of ureteral stent usage. In this article we review the currently applied novel ideas and new designs of ureteral stents. Moreover, we evaluate potential future prospects of ureteral stent development adopted mostly by the pioneering cardiovascular stent industry, focusing, however, on the differences between ureteral and endothelial tissue.

摘要

输尿管支架是一种微创替代方法,可在输尿管通畅性恶化或由于外在或内在病因而有明显阻塞风险时保留尿液引流。理想的支架应具有完美的长期疗效,且无支架相关并发症,但目前仍缺乏这种支架,并且支架使用会引起多种不良反应,限制了其作为长期尿液引流工具的价值。目前正在评估一些关于支架设计、组成材料和支架涂层的新想法,以期消除输尿管支架使用的上述缺点。本文综述了目前应用的新型输尿管支架的想法和设计。此外,我们还评估了输尿管支架发展的潜在未来前景,主要借鉴了开创性的心血管支架行业的经验,但重点关注输尿管和内皮组织之间的差异。

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本文引用的文献

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A novel drug eluting ureteral stent: a prospective, randomized, multicenter clinical trial to evaluate the safety and effectiveness of a ketorolac loaded ureteral stent.一种新型药物洗脱输尿管支架:一项前瞻性、随机、多中心临床试验,旨在评估载有酮咯酸的输尿管支架的安全性和有效性。
J Urol. 2010 Mar;183(3):1037-42. doi: 10.1016/j.juro.2009.11.035. Epub 2010 Jan 21.
2
Polymers as ureteral stents.聚合物作为输尿管支架。
J Endourol. 2010 Feb;24(2):191-8. doi: 10.1089/end.2009.0516.
3
Next generation biodegradable ureteral stent in a yucatan pig model.在猪模型中进行下一代可生物降解输尿管支架的研究。
J Urol. 2010 Feb;183(2):765-71. doi: 10.1016/j.juro.2009.09.073.
4
Evaluation of symptoms and patients' comfort for JJ-ureteral stents with and without antireflux-membrane valve.评价 JJ 输尿管支架带与不带反流膜阀的症状和患者舒适度。
Urology. 2010 Jan;75(1):212-6. doi: 10.1016/j.urology.2009.07.1258. Epub 2009 Oct 12.
5
XTENT(R) Custom NX drug eluting stent systems.
EuroIntervention. 2007 May;3(1):158-61.
6
Uropathogen interaction with the surface of urological stents using different surface properties.尿路病原体与具有不同表面特性的泌尿外科支架表面的相互作用。
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