Hahn Paul, Migacz Justin, O'Connell Rachelle, Maldonado Ramiro S, Izatt Joseph A, Toth Cynthia A
Departments of Ophthalmology and Biomedical Engineering, Duke University, Durham, North Carolina, USA.
Ophthalmic Surg Lasers Imaging. 2011 Jul;42 Suppl(0):S85-94. doi: 10.3928/15428877-20110627-08.
Optical coherence tomography (OCT) has transformed diagnostic ophthalmic imaging but until recently has been limited to the clinic setting. The development of spectral-domain OCT (SD-OCT), with its improved speed and resolution, along with the development of a handheld OCT scanner, enabled portable imaging of patients unable to sit in a conventional tabletop scanner. This handheld SD-OCT unit has proven useful in examinations under anesthesia and, more recently, in intraoperative imaging of preoperative and postoperative manipulations. Recently, several groups have pioneered the development of novel OCT modalities, such as microscope-mounted OCT systems. Although still immature, the development of these systems is directed toward real-time imaging of surgical maneuvers in the intraoperative setting. This article reviews intraoperative imaging of the posterior and anterior segment using the handheld SD-OCT and recent advances toward real-time microscope-mounted intrasurgical imaging.
光学相干断层扫描（OCT）已经改变了眼科诊断成像，但直到最近它还仅限于临床环境。光谱域OCT（SD - OCT）的发展，其速度和分辨率得到了提高，同时手持式OCT扫描仪的发展，使得无法坐在传统台式扫描仪上的患者能够进行便携式成像。这种手持式SD - OCT设备已被证明在麻醉下检查中有用，最近，在术前和术后操作的术中成像中也很有用。最近，几个研究小组率先开发了新型OCT模式，如显微镜安装的OCT系统。尽管这些系统仍不成熟，但其发展方向是术中实时成像手术操作。本文回顾了使用手持式SD - OCT对眼后段和前段进行术中成像以及显微镜安装的术中实时成像的最新进展。
