Department of Pharmacognosy, Faculty of Pharmacy, Mansoura University, Mansoura 35516, Egypt.
Nat Prod Res. 2012;26(14):1328-33. doi: 10.1080/14786419.2011.582841. Epub 2011 Jul 27.
Two new compounds: 3-β,15-α,23,28-tetrahydroxyolean-12-en-3-O-arabinopyaranoside and 3-β,23,28-trihydroxy-olean-12-en-3-O-β-D-glucopyranoside were isolated from the aerial parts of Ammania auriculata along with the known compounds kaempferol, β-sitosterol-3-O-β- D-glucoside, 2-α,3-β,23-trihydroxyolean-12-en-28-oic acid-28-O-β-D-glucopyranoside, quercetin, kaempferol-3-O-α-L-arabinofuranoside, kaempferol-3-O-β-D-xylopyranoside and ellagic acid. Structures of these compounds were elucidated on the basis of their spectroscopic data (NMR, UV, MS and IR spectra). The antioxidant activities of the total extract, the fractions CH(2)Cl(2), EtOAc and the remaining aqueous together with the compounds 1, 6 and 9 were comparable with that of the standard antioxidant, ascorbic acid.
3-β,15-α,23,28-四羟基齐墩果-12-烯-3-O-阿拉伯吡喃糖苷和 3-β,23,28-三羟基齐墩果-12-烯-3-O-β-D-吡喃葡萄糖苷,以及已知化合物山柰酚、β-谷甾醇-3-O-β-D-葡萄糖苷、2-α,3-β,23-三羟基齐墩果-12-烯-28-酸-28-O-β-D-吡喃葡萄糖苷、槲皮素、山柰酚-3-O-α-L-阿拉伯呋喃糖苷、山柰酚-3-O-β-D-吡喃木糖苷和鞣花酸。这些化合物的结构是根据其光谱数据(NMR、UV、MS 和 IR 光谱)确定的。总提取物、CH(2)Cl(2)、EtOAc 馏分和剩余水相与化合物 1、6 和 9 的抗氧化活性与标准抗氧化剂抗坏血酸相当。