Faculty of Mechanical Engineering, Czech Technical University in Prague, Prague, Czech Republic.
Forensic Sci Int. 2012 Jan 10;214(1-3):18-22. doi: 10.1016/j.forsciint.2011.07.007. Epub 2011 Jul 26.
It is a well-known fact that the length of an artery in situ and the length of an excised artery differs. Retraction of blood vessels is usually observed. This pre-tension plays crucial role in arterial biomechanics. It augments an artery wall load-bearing capacity. This paper presents the longitudinal pre-strain of the human aorta as an index of human age. The length of abdominal aortas was measured during autopsies before and after segment resection. The longitudinal pre-strain was calculated in 130 donors; 100 male and 30 female bodies. The pre-strain was defined as the ratio between in situ length and the length after the excision. The mean pre-strain was found to be 1.18±0.10 for male and 1.14±0.10 for female sample (mean±standard deviation). The age in the male group was 41.6±15.9 years; and 47.7±17.7 years in the female group. Statistical analysis revealed the correlation coefficient between age and pre-strain r=-0.821 and r=-0.839 in male and female group, respectively. The analysis also confirmed close correlation between aortic circumference and age; and between circumference and pre-strain. Linear and power law regression equations were employed and prediction intervals were computed. The power law estimates the age more accurately than linear one model. Nevertheless, especially for small values of the pre-strain (aged individuals) the linear model can be advantageous.
众所周知，原位动脉长度和切除动脉长度不同。通常会观察到血管回缩。这种预张力在动脉生物力学中起着至关重要的作用。它增加了动脉壁的承载能力。本文提出了以人类主动脉的纵向预应变作为人类年龄的指标。在尸检前和节段切除后测量腹主动脉的长度。在 130 名供体中计算了纵向预应变；100 名男性和 30 名女性。预应变定义为原位长度与切除后长度的比值。男性样本的平均预应变为 1.18±0.10，女性样本的平均预应变为 1.14±0.10（平均值±标准差）。男性组的年龄为 41.6±15.9 岁；女性组的年龄为 47.7±17.7 岁。统计分析显示，年龄与预应变成负相关，男性组的相关系数 r=-0.821，女性组的相关系数 r=-0.839。分析还证实了主动脉周长与年龄之间存在密切相关性；以及周长与预应变成正相关。采用线性和幂律回归方程，并计算了预测区间。幂律模型比线性模型更准确地估计年龄。然而，特别是对于预应变较小的值（年龄较大的个体），线性模型可能更有利。
