Emergency Care, Critical Care Medicine, Pain Medicine and Anesthesiology Department, Tor Vergata Polyclinic, University of Tor Vergata, Rome, Italy.
Eur Rev Med Pharmacol Sci. 2011 Jun;15(6):682-94.
Since its introduction in the 1950s, the use of mesotherapy has generated much interest among clinicians and patients. The Italian Society of Mesotherapy (SIM) brought together a panel of experts to review available evidence and to draw up a series of recommendations on the use of intradermal therapy (LIT) in clinical practice.
There was overwhelming agreement among Consensus Group members that, when used correctly, LIT is a valuable therapeutic option in the treatment of painful, loco-regional conditions. They also emphasised that the clinical efficacy of LIT has been demonstrated in the management of chronic venous lymphatic insufficiency, oedematous fibrosclerotic panniculopathy and facial skin aging. The experts were unanimous on the use of LIT in vaccination. Mesotherapy is not a substitute for other therapeutic options and should only be used when the patient has been fully informed of its advantages and limitations. Likewise the procedure should only be carried out by an experienced qualified physician.
Although there was widespread agreement among the Consensus Group on the place of LIT in several indications, the Authors reiterated the need for more large-scale clinical trials to determine the specific benefits and limitations in some areas of the application of intradermal therapy.
自 20 世纪 50 年代问世以来，中胚层疗法的应用在临床医生和患者中引起了极大的兴趣。意大利中胚层疗法学会（SIM）召集了一组专家，对现有证据进行了审查，并就真皮内疗法（LIT）在临床实践中的应用制定了一系列建议。
共识小组成员一致认为，当正确使用时，LIT 是治疗疼痛、局部疾病的一种有价值的治疗选择。他们还强调，LIT 在慢性静脉淋巴功能不全、水肿性纤维硬化性脂膜炎和面部皮肤老化的治疗中已显示出临床疗效。专家组一致认为 LIT 可用于疫苗接种。中胚层疗法不能替代其他治疗选择，只有在患者充分了解其优缺点的情况下才能使用。同样，该程序只能由经验丰富的合格医生进行。
尽管共识小组成员对 LIT 在几种适应证中的地位达成了广泛共识，但作者重申需要进行更多的大规模临床试验，以确定在真皮内疗法应用的某些领域的具体益处和局限性。
