Primary Care Unit ASL RM 1, Rome.
San Marco Hospice and Palliative Care, Latina.
Clin Ter. 2021 Jan-Feb;171(1):e37-e45. doi: 10.7417/CT.2021.2278.
Mesotherapy, also known as local intradermal therapy, widely used all over the world, is a technique used to inject substances into the surface layer of the skin. There are no international guidelines for the correct use of this technique and in many countries, it is still applied empirically without valid patient consent. The Italian society of mesotherapy has planned a study to assess the rationale and clinical applications based on current evidence.
An independent steering committee, based on the available scientific literature, has formulated a series of clinical questions. 21 experts responded by writing an evidence-based document. From this document 30 statements were obtained which were presented to 114 experts using the Delphi method.
28 statements reached a broad agreement on definition, technique, pharmacological rationale, indications and some crucial ethical aspect.
Although further studies are needed to establish the clinical role of this technique in each field of application, our statements recommend the correct application according to the needs of the individual patient in full respect of ethics.
中胚层疗法，又称局部真皮内疗法，在全世界广泛应用，是一种将物质注入皮肤表层的技术。目前，尚无关于正确使用该技术的国际指南，在许多国家，该技术仍在未经患者有效同意的情况下凭经验使用。意大利中胚层疗法学会计划开展一项研究，根据现有证据评估其基本原理和临床应用。
一个独立的指导委员会根据现有科学文献制定了一系列临床问题。21 名专家通过撰写循证文件做出了回应。从这份文件中得出 30 个陈述，并使用德尔菲法向 114 名专家进行了陈述。
28 个陈述在定义、技术、药理学原理、适应证和一些关键伦理方面达成了广泛共识。
尽管需要进一步的研究来确定该技术在每个应用领域的临床作用，但我们的陈述建议根据每个患者的具体需求，在充分尊重伦理的前提下，正确应用该技术。
