简便的一锅法合成具有增强载药能力的聚合物-磷脂复合微泡用于超声触发治疗
Facile One-Pot Synthesis of Polymer-Phospholipid Composite Microbubbles with Enhanced Drug Loading Capacity for Ultrasound-Triggered Therapy.
作者信息
Nakatsuka Matthew A, Lee Joo Hye, Nakayama Emi, Hung Albert M, Hsu Mark J, Mattrey Robert F, Esener Sadik C, Cha Jennifer N, Goodwin Andrew P
机构信息
University of California, San Diego, Department of Nanoengineering, 9500 Gilman Dr. #0048, La Jolla, CA 92093, USA.
出版信息
Soft Matter. 2011;2011(7):1656-1659. doi: 10.1039/C0SM01131B.
Abstract
This paper reports the one-pot synthesis of perfluorocarbon microbubbles with crosslinked shells of poly(acrylic acid) and phospholipid that boast excellent ultrasound contrast enhancement, enhanced loading capacity, and the ability to retain or release their contents through variation in the level of ultrasound exposure.
摘要
本文报道了一种全氟化碳微泡的一锅法合成，其具有由聚丙烯酸和磷脂构成的交联壳层，具备优异的超声造影增强效果、更高的负载能力，以及能够通过改变超声暴露水平来保留或释放其内容物的能力。
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本文引用的文献
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