Tennent-Brown Brett S, Koenig Amie, Williamson Lisa H, Boston Raymond C
Department of Large Animal Medicine, College of Veterinary Medicine, University of Georgia, Athens, GA 30602, USA.
J Am Vet Med Assoc. 2011 Aug 1;239(3):380-6. doi: 10.2460/javma.239.3.380.
To compare the performance of 3 point-of-care glucose meters in adult and juvenile alpacas with that of a laboratory-based analyzer.
Evaluation study.
35 adult alpacas and 21 juvenile alpacas.
Whole blood samples obtained via jugular venipuncture were tested with all 3 point-of-care glucose meters; plasma samples were also tested with 1 of those meters. Glucose concentrations determined by use of the point-of-care meters were compared with results from the laboratory-based analyzer.
Plasma glucose concentrations determined by use of the laboratory-based analyzer ranged from 36 to 693 mg/dL. Over the entire range of glucose concentrations tested, the Lin concordance correlation coefficient (agreement) was significant and excellent for all comparisons. Concordance decreased for 1 glucometer when testing whole blood samples over a narrower range of glucose concentrations (50 to 200 mg/dL). Bias was typically small (< 10 mg/dL) for 3 of the 4 comparisons but considerable for 1 meter with the use of whole blood. The limits of agreement were wide for all comparisons over the entire range of glucose concentrations tested but decreased to within acceptable limits when the narrower glucose range (50 to 200 mg/dL) was analyzed for 3 of the comparisons. For samples with a PCV < 25%, bias and the limits of agreement were greater for one of the meters tested.
Discrepancies between point-of-care glucose meters and reference techniques can be considerable in alpacas, emphasizing the importance of assessing individual meter performance in a target population.
比较3种即时血糖仪在成年和幼年羊驼中的性能与实验室分析仪的性能。
评估研究。
35只成年羊驼和21只幼年羊驼。
通过颈静脉穿刺采集的全血样本用所有3种即时血糖仪进行检测；血浆样本也用其中1种血糖仪进行检测。将即时血糖仪测定的葡萄糖浓度与实验室分析仪的结果进行比较。
使用实验室分析仪测定的血浆葡萄糖浓度范围为36至693mg/dL。在测试的整个葡萄糖浓度范围内，所有比较的线性一致性相关系数（一致性）均显著且良好。当在较窄的葡萄糖浓度范围（50至200mg/dL）内检测全血样本时，1种血糖仪的一致性降低。4种比较中有3种的偏差通常较小（<10mg/dL），但使用全血时1种血糖仪的偏差较大。在测试的整个葡萄糖浓度范围内，所有比较的一致性界限都很宽，但对其中3种比较在分析较窄的葡萄糖范围（50至200mg/dL）时，一致性界限降至可接受范围内。对于PCV<25%的样本，所测试的1种血糖仪的偏差和一致性界限更大。
即时血糖仪与参考技术之间的差异在羊驼中可能相当大，强调了在目标群体中评估单个血糖仪性能的重要性。
