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用于快速测定犬血乳酸浓度的四种即时检测血糖仪的评估。

Evaluation of four point-of-care meters for rapid determination of blood lactate concentrations in dogs.

作者信息

Acierno Mark J, Mitchell Mark A

机构信息

Department of Veterinary Clinical Science, School of Veterinary Medicine, Louisiana State University, Baton Rouge, LA 70810, USA.

出版信息

J Am Vet Med Assoc. 2007 May 1;230(9):1315-8. doi: 10.2460/javma.230.9.1315.

Abstract

OBJECTIVE

To determine whether blood lactate values determined in dogs with 4 commercially available point-of-care meters were in agreement with values determined with a critical care laboratory blood analyzer.

DESIGN

Prospective study.

ANIMALS

50 dogs evaluated for emergency treatment.

PROCEDURES

Blood samples were collected at initial evaluation and processed on 4 point-of-care meters and on a critical care laboratory blood analyzer.

RESULTS

All 4 point-of-care lactate meters generated measurements that were in agreement with the hospital's critical care analyzer. Values for agreement (bias) between the 4 point-of-care meters and the critical care analyzer were -0.652 (limits of agreement [LA], -1.958 to 0.654]), -0.670 (LA, -2.110 to 0.769), -0.096 (LA, -2.071 to 1.879), and -0.498 (LA, -2.616 to 1.620), respectively.

CONCLUSIONS AND CLINICAL RELEVANCE

Despite its prognostic and therapeutic relevance, blood lactate measurement in dogs has been hampered by the inability to perform the test in a timely fashion. Results of the present study indicated that several handheld point-of-care lactate meters provided results that were in agreement with a laboratory critical care blood analyzer.

摘要

目的

确定使用4种市售即时检验血糖仪测定的犬血乳酸值是否与使用重症监护实验室血液分析仪测定的值一致。

设计

前瞻性研究。

动物

50只接受急诊治疗评估的犬。

方法

在初次评估时采集血样,并在4种即时检验血糖仪和一台重症监护实验室血液分析仪上进行检测。

结果

所有4种即时检验乳酸血糖仪所测结果均与医院的重症监护分析仪一致。4种即时检验血糖仪与重症监护分析仪之间的一致性(偏差)值分别为-0.652(一致性界限[LA],-1.958至0.654)、-0.670(LA,-2.110至0.769)、-0.096(LA,-2.071至1.879)和-0.498(LA,-2.616至1.620)。

结论及临床意义

尽管血乳酸测定对犬的预后和治疗具有重要意义,但由于无法及时进行检测,犬血乳酸测定一直受到阻碍。本研究结果表明,几种手持式即时检验乳酸血糖仪所提供的结果与实验室重症监护血液分析仪一致。

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