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神经毒理学中认知评估的简要回顾。

A brief review of cognitive assessment in neurotoxicology.

机构信息

Department of Neurology, University of Kentucky College of Medicine, 740 South Limestone Street, Suite L445, Lexington, KY 40536-0284, USA.

出版信息

Neurol Clin. 2011 Aug;29(3):581-90. doi: 10.1016/j.ncl.2011.05.008. Epub 2011 Jun 24.

Abstract

Among commercial and industrial chemicals, cosmetics, food additives, pesticides, and medicinal drugs, there are more than 50,000 substances distributed. Neurotoxic insults to the brain can manifest in many different ways, especially involving cognition. Given many possible differences in the pathophysiology of neurotoxic exposure and related cognitive sequelae, a systematic method of cognitive assessment is important for appropriate management of neurotoxic exposure. In the context of Neurotoxicology, this article briefly reviews the contemporary literature and the utility of cognitive assessment tools that are used in neuropsychology.

摘要

在商业和工业化学品、化妆品、食品添加剂、农药和药物中,分布着超过 50000 种物质。神经毒性对大脑的影响可能表现为多种不同的方式,特别是涉及认知。鉴于神经毒性暴露和相关认知后果的病理生理学可能存在许多差异,认知评估的系统方法对于适当管理神经毒性暴露非常重要。本文简要回顾了神经毒理学领域的当代文献,以及神经心理学中使用的认知评估工具的效用。

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