• 文献检索
  • 文档翻译
  • 深度研究
  • 学术资讯
  • Suppr Zotero 插件Zotero 插件
  • 邀请有礼
  • 套餐&价格
  • 历史记录
应用&插件
Suppr Zotero 插件Zotero 插件浏览器插件Mac 客户端Windows 客户端微信小程序
定价
高级版会员购买积分包购买API积分包
服务
文献检索文档翻译深度研究API 文档MCP 服务
关于我们
关于 Suppr公司介绍联系我们用户协议隐私条款
关注我们

Suppr 超能文献

核心技术专利：CN118964589B侵权必究
粤ICP备2023148730 号-1Suppr @ 2026

文献检索

告别复杂PubMed语法，用中文像聊天一样搜索，搜遍4000万医学文献。AI智能推荐，让科研检索更轻松。

立即免费搜索

文件翻译

保留排版，准确专业，支持PDF/Word/PPT等文件格式，支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述，25分钟生成高质量综述，智能提取关键信息，辅助科研写作。

立即免费体验

肾移植术后患者并发神经感染的双侧急性视网膜坏死。

Bilateral acute retinal necrosis associated with neuroinfection in patient after renal transplantation.

机构信息

Department of Ophthalmology, Medical University of Warsaw, Warsaw, Poland.

出版信息

Med Sci Monit. 2011 Aug;17(8):CS99-102. doi: 10.12659/msm.881890.

DOI:10.12659/msm.881890
PMID:21804470
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC3539611/
Abstract

BACKGROUND

Acute retinal necrosis (ARN) is characterized by the triad of acute vitritis, peripheral necrotizing retinitis and vasculitis.

CASE REPORT

We report a case of 54-year-old woman with bilateral acute retinal necrosis associated with neuroinfection. Her past medical history included renal transplantation, hypertension and aortic stenosis. Observational case report: Diagnostic investigations included biochemical tests, lumbar puncture, eye ultrasonography and MRI of the brain. Anti-HSV IgG antibody titers were elevated in the blood and cerebrospinal fluid. In MRI T2-mode, inflammatory changes were found in the white matter of the right hemisphere. The patient was treated with systemic acyclovir, itraconazole, metronidazole and ciprofloxacin for 3 weeks. Retinal detachment was observed in both eyes.

CONCLUSIONS

Acute retinal necrosis can be the single manifestation of herpes virus reactivation in patients after organ transplantation.

摘要

背景

急性视网膜坏死（ARN）的特征是三联征，包括急性眼炎、周边坏死性视网膜炎和血管炎。

病例报告

我们报告了一例 54 岁女性双侧急性视网膜坏死伴神经感染。她的既往病史包括肾移植、高血压和主动脉瓣狭窄。观察性病例报告：诊断性检查包括生化检查、腰椎穿刺、眼部超声和脑部 MRI。血液和脑脊液中的抗单纯疱疹病毒 IgG 抗体滴度升高。在 MRI T2 模式中，发现右侧大脑半球白质有炎症改变。患者接受了全身性阿昔洛韦、伊曲康唑、甲硝唑和环丙沙星治疗 3 周。双眼均出现视网膜脱离。

结论

急性视网膜坏死可能是器官移植后疱疹病毒再激活的单一表现。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/a83e/3539611/d767a47d60f4/medscimonit-17-8-CS99-g003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/a83e/3539611/eed68bb3040f/medscimonit-17-8-CS99-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/a83e/3539611/bdb1ee8e6c88/medscimonit-17-8-CS99-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/a83e/3539611/d767a47d60f4/medscimonit-17-8-CS99-g003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/a83e/3539611/eed68bb3040f/medscimonit-17-8-CS99-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/a83e/3539611/bdb1ee8e6c88/medscimonit-17-8-CS99-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/a83e/3539611/d767a47d60f4/medscimonit-17-8-CS99-g003.jpg

相似文献

1
Bilateral acute retinal necrosis associated with neuroinfection in patient after renal transplantation.肾移植术后患者并发神经感染的双侧急性视网膜坏死。
Med Sci Monit. 2011 Aug;17(8):CS99-102. doi: 10.12659/msm.881890.
2
[Atypical case of acute retinal necrosis secondary to the primary herpes simplex infection].[原发性单纯疱疹感染继发急性视网膜坏死的非典型病例]
Klin Oczna. 2015;117(3):184-8.
3
Herpes simplex encephalitis and bilateral acute retinal necrosis syndrome after craniotomy.开颅术后的单纯疱疹病毒性脑炎和双侧急性视网膜坏死综合征
Am J Ophthalmol. 1998 Sep;126(3):456-60. doi: 10.1016/s0002-9394(98)00108-1.
4
[Bilateral acute retinal necrosis syndrome associated with meningoencephalitis caused by herpes simplex virus 2. A case report].[双侧急性视网膜坏死综合征合并单纯疱疹病毒2型所致脑膜脑炎。1例病例报告]
J Fr Ophtalmol. 2004 Sep;27(7):795-800. doi: 10.1016/s0181-5512(04)96216-x.
5
Acute retinal necrosis caused by reactivation of herpes simplex virus type 2.由2型单纯疱疹病毒再激活引起的急性视网膜坏死。
Am J Ophthalmol. 1994 Aug 15;118(2):205-11. doi: 10.1016/s0002-9394(14)72900-9.
6
Viral causes of the acute retinal necrosis syndrome.急性视网膜坏死综合征的病毒病因
Am J Ophthalmol. 2000 Feb;129(2):166-72. doi: 10.1016/s0002-9394(99)00316-5.
7
Progressive outer retinal necrosis caused by herpes simplex virus type 1 in a patient with acquired immunodeficiency syndrome.1型单纯疱疹病毒引起的获得性免疫缺陷综合征患者的进行性外层视网膜坏死。
Ophthalmology. 2000 Apr;107(4):790-4. doi: 10.1016/s0161-6420(99)00143-8.
8
Acute retinal necrosis features, management, and outcomes.急性视网膜坏死的特征、治疗及预后。
Ophthalmology. 2007 Apr;114(4):756-62. doi: 10.1016/j.ophtha.2006.08.037. Epub 2006 Dec 20.
9
Clinical characteristics of acute HSV-2 retinal necrosis.急性单纯疱疹病毒2型视网膜坏死的临床特征
Am J Ophthalmol. 2004 May;137(5):872-9. doi: 10.1016/j.ajo.2003.12.036.
10
Acute retinal necrosis secondary to herpes simplex virus type 2 in neonates.新生儿2型单纯疱疹病毒继发的急性视网膜坏死
Ophthalmic Surg Lasers Imaging Retina. 2015 Apr;46(4):499-501. doi: 10.3928/23258160-20150422-18.

引用本文的文献

1
A Case of Frosted Branch Angiitis in the Age of Polymerase Chain Reaction: Diagnostic and Therapeutic Considerations.聚合酶链反应时代的一例霜样树枝状视网膜血管炎：诊断与治疗考量
Cureus. 2022 Sep 5;14(9):e28816. doi: 10.7759/cureus.28816. eCollection 2022 Sep.
2
A Comprehensive Update on Retinal Vasculitis: Etiologies, Manifestations and Treatments.视网膜血管炎综合更新：病因、表现及治疗
J Clin Med. 2022 Apr 30;11(9):2525. doi: 10.3390/jcm11092525.
3
Clinical manifestation of self-limiting acute retinal necrosis.自限性急性视网膜坏死的临床表现。

本文引用的文献

1
Retinal complications in patients with solid organ or bone marrow transplantations.实体器官或骨髓移植患者的视网膜并发症
Transplantation. 2007 Mar 27;83(6):694-9. doi: 10.1097/01.tp.0000259386.59375.8a.
2
[Bilateral acute retinal necrosis syndrome associated with meningoencephalitis caused by herpes simplex virus 2. A case report].[双侧急性视网膜坏死综合征合并单纯疱疹病毒2型所致脑膜脑炎。1例病例报告]
J Fr Ophtalmol. 2004 Sep;27(7):795-800. doi: 10.1016/s0181-5512(04)96216-x.
3
[Herpes simplex virus type 1 acute retinal necrosis two years after presumably herpetic meningoencephalitis].
Med Sci Monit. 2014 Oct 30;20:2088-96. doi: 10.12659/MSM.890469.
[疑似疱疹性脑膜炎两年后发生的单纯疱疹病毒1型急性视网膜坏死]
Arch Soc Esp Oftalmol. 2004 Jan;79(1):33-5. doi: 10.4321/s0365-66912004000100008.
4
Ocular complications of heart, lung, and liver transplantation.心脏、肺和肝移植的眼部并发症。
Br J Ophthalmol. 1998 Apr;82(4):423-8. doi: 10.1136/bjo.82.4.423.
5
Standard diagnostic criteria for the acute retinal necrosis syndrome. Executive Committee of the American Uveitis Society.急性视网膜坏死综合征的标准诊断标准。美国葡萄膜炎学会执行委员会。
Am J Ophthalmol. 1994 May 15;117(5):663-7. doi: 10.1016/s0002-9394(14)70075-3.
6
Acute retinal necrosis syndrome.急性视网膜坏死综合征
Br J Ophthalmol. 1991 May;75(5):292-7. doi: 10.1136/bjo.75.5.292.