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Fospropofol: clinical pharmacology.

作者信息

Bengalorkar Girish M, Bhuvana K, Sarala N, Kumar Tn

机构信息

Assistant Professor, Department of Pharmacology, Sri Devaraj Urs Medical College, Tamaka, Kolar 563101, India.

出版信息

J Anaesthesiol Clin Pharmacol. 2011 Jan;27(1):79-83.

PMID:21804712
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC3146164/
Abstract
摘要
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/1a43/3146164/14f44f7b1f81/JOACP-27-79-g005.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/1a43/3146164/9b051c83d9c5/JOACP-27-79-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/1a43/3146164/c90998580d77/JOACP-27-79-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/1a43/3146164/14f44f7b1f81/JOACP-27-79-g005.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/1a43/3146164/9b051c83d9c5/JOACP-27-79-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/1a43/3146164/c90998580d77/JOACP-27-79-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/1a43/3146164/14f44f7b1f81/JOACP-27-79-g005.jpg

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The unseen animal behind medicine: exploring considerations of animal-derived medications and anaesthetics in today's landscape.

本文引用的文献

1
Safety evaluation of fospropofol for sedation during minor surgical procedures.在小型外科手术中镇静时福司泊酚的安全性评价。
J Clin Anesth. 2010 Jun;22(4):260-7. doi: 10.1016/j.jclinane.2009.08.007.
2
Sedation and analgesia in gastrointestinal endoscopy: what's new?胃肠内镜中的镇静与镇痛：有哪些新进展？
World J Gastroenterol. 2010 May 28;16(20):2451-7. doi: 10.3748/wjg.v16.i20.2451.
3
Fospropofol.福司泊氟酯。
医学背后看不见的动物：探索当今环境下对动物源性药物和麻醉剂的考量。
BJA Open. 2024 Dec 16;13:100360. doi: 10.1016/j.bjao.2024.100360. eCollection 2025 Mar.
4
Efficacy and safety of fospropofol disodium sedation for same-day bidirectional endoscopy in elderly patients: protocol for a prospective, single-center, randomized, double-blind, non-inferiority trial.老年患者同日双向内镜检查中丙泊酚二钠镇静的有效性和安全性：一项前瞻性、单中心、随机、双盲、非劣效性试验方案
Front Pharmacol. 2024 Aug 8;15:1378081. doi: 10.3389/fphar.2024.1378081. eCollection 2024.
5
Structural Modification in Anesthetic Drug Development for Prodrugs and Soft Drugs.用于前药和软药的麻醉药物开发中的结构修饰
Front Pharmacol. 2022 Jul 1;13:923353. doi: 10.3389/fphar.2022.923353. eCollection 2022.
6
Efficacy and Safety of Fospropofol Disodium for Injection in General Anesthesia Induction for Adult Patients: A Phase 3 Trial.注射用磷丙泊酚二钠用于成年患者全身麻醉诱导的有效性和安全性：一项3期试验。
Front Pharmacol. 2021 Sep 13;12:687894. doi: 10.3389/fphar.2021.687894. eCollection 2021.
7
Metabolic Profiles of Propofol and Fospropofol: Clinical and Forensic Interpretative Aspects.丙泊酚和福泊酚的代谢谱：临床和法医解释方面。
Biomed Res Int. 2018 May 24;2018:6852857. doi: 10.1155/2018/6852857. eCollection 2018.
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Pharmacologic Considerations for Pediatric Sedation and Anesthesia Outside the Operating Room: A Review for Anesthesia and Non-Anesthesia Providers.手术室以外的儿科镇静与麻醉的药理学考量：给麻醉与非麻醉医护人员的综述
Paediatr Drugs. 2017 Oct;19(5):435-446. doi: 10.1007/s40272-017-0241-5.
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Pain on propofol injection: Causes and remedies.丙泊酚注射时的疼痛：原因与对策。
Indian J Pharmacol. 2016 Nov-Dec;48(6):617-623. doi: 10.4103/0253-7613.194845.
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4
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Ther Clin Risk Manag. 2009;5:949-59. doi: 10.2147/tcrm.s5583. Epub 2009 Dec 29.
5
A randomized, double-blind, phase 3 study of fospropofol disodium for sedation during colonoscopy.一项关于双盲、随机、3 期临床试验的研究，研究对象为福司泊氟酯在结肠镜检查镇静中的应用。
J Clin Gastroenterol. 2010 May-Jun;44(5):345-53. doi: 10.1097/MCG.0b013e3181c2987e.
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Fospropofol disodium, a water-soluble prodrug of the intravenous anesthetic propofol (2,6-diisopropylphenol).磷丙泊酚二钠，静脉麻醉药丙泊酚（2,6 - 二异丙基苯酚）的水溶性前体药物。
Expert Opin Investig Drugs. 2009 Oct;18(10):1565-71. doi: 10.1517/13543780903193063.
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AANA J. 2009 Aug;77(4):301-8.
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Fospropofol disodium injection for the sedation of patients undergoing colonoscopy.注射用福司泊氟烷双钠盐用于结肠镜检查患者的镇静。
Ther Clin Risk Manag. 2008 Aug;4(4):733-8. doi: 10.2147/tcrm.s3091.
9
A phase 3, randomized, double-blind study to assess the efficacy and safety of fospropofol disodium injection for moderate sedation in patients undergoing flexible bronchoscopy.一项评估磷丙泊酚二钠注射液用于可弯曲支气管镜检查患者中度镇静的疗效和安全性的3期随机双盲研究。
Chest. 2009 Jan;135(1):41-47. doi: 10.1378/chest.08-0623. Epub 2008 Jul 18.
10
Your prodrug releases formaldehyde: should you be concerned? No!你的前药会释放甲醛：你应该担心吗？不！
J Pharm Sci. 2008 Oct;97(10):4184-93. doi: 10.1002/jps.21319.