Department Chemie and Catalysis Research Center, Technische Universität München, Lichtenbergstr. 4, 85747 Garching, Germany.
Beilstein J Org Chem. 2011;7:847-59. doi: 10.3762/bjoc.7.97. Epub 2011 Jun 22.
Gold catalysis has emerged as one of the most dynamic fields in organic synthesis. Only recently, more and more domino processes, for which gold pre-catalysts were found to be outstandingly effective, were paralleled by employing iodine electrophiles in place of gold compounds. This review highlights how, in certain cases, iodonium activation can match gold-catalyzed reactions to construct identical product scaffolds. Likewise, processes are discussed where mostly identical starting materials are transformed into diverse frameworks depending on whether gold or iodonium activation was used to trigger the reaction.
金催化已成为有机合成中最具活力的领域之一。就在最近，越来越多的多米诺反应采用碘代亲电试剂代替金化合物，而金预催化剂在这些反应中被证明非常有效。本文综述了在某些情况下，碘鎓活化可以与金催化反应相匹配，构建相同的产物骨架。同样，本文还讨论了在大多数情况下，相同的起始原料根据所使用的金或碘鎓活化来触发反应，转化为不同的骨架。
