Department of Infectious Diseases, Singapore General Hospital, Outram Road, Singapore 169608.
Singapore Med J. 2011 Jul;52(7):e160-2.
Cryptococcosis is an invasive fungal infection that occurs worldwide. Infections caused by Cryptococcus (C.) neoformans are commonly associated with immunocompromised patients, while those caused by C. gattii predominantly affect immunocompetent hosts. However, the latter has also been increasingly reported in immunocompromised patients such as those with HIV. Cutaneous involvement by C. gattii in immunocompetent patients is a rare manifestation, with only a few cases reported worldwide. C. gattii infection has rarely been reported in Singapore, with all three reported cases presenting as meningitis in immunocompetent individuals. Its natural habitat is the Eucalyptus tree, which is common in Singapore. We report the case of a 37-year-old migrant worker who had primary cutaneous infection due to C. gattii after sustaining traumatic inoculation.
隐球菌病是一种全球性的侵袭性真菌感染。新型隐球菌（C. neoformans）引起的感染通常与免疫功能低下的患者有关，而荚膜组织胞浆菌（C. gattii）引起的感染主要影响免疫功能正常的宿主。然而，后者也越来越多地在免疫功能低下的患者中被报道，如 HIV 感染者。荚膜组织胞浆菌引起的免疫功能正常患者的皮肤感染是一种罕见的表现，全球仅有少数几例报道。荚膜组织胞浆菌感染在新加坡很少见，所有报告的三例均为免疫功能正常个体的脑膜炎。其自然栖息地是桉树，新加坡很常见。我们报告了一例 37 岁的移民工人，他因创伤接种后发生原发性皮肤感染。
