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[Study on purification of strictosamide from Nauclea officinalis by macroporous resin].

作者信息

Meng Zhaoqing, Ding Gang, Liu Yujie, Xu Jia, Liu Wenjun, Xiao Wei

机构信息

Jiangsu Zeukov Pharmaceutical S&T Inc., Nanjing 210017, China.

出版信息

Zhongguo Zhong Yao Za Zhi. 2011 Apr;36(8):1007-10.

Abstract

OBJECTIVE

To study on the purification of strictosamide from Nauclea officinalis by macroporous resin to provide reference for production.

METHOD

The best macroporous resin was selected among 10 kinds of resins according to adsorption and desorption of the static adsorption experiments. The adsorption quantity, elution volume of water, concentration and elution volume of alcohol were determined according to the single factor experiment.

RESULT

HPD400 was the best resin, and the best adsorption quantity was 20.23 mg x g(-1), the elution volume of water and 30% alcohol was 6 BV, and the elution volume of 70% alcohol was 4 BV.

CONCLUSION

This technology is simple, feasible, and it can provide reference for the industrialized production.

摘要

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