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急性植物中毒:临床特征和暴露情况分析。

Acute plant poisoning: analysis of clinical features and circumstances of exposure.

机构信息

Swiss Toxicological Information Centre, Zurich, Switzerland.

出版信息

Clin Toxicol (Phila). 2011 Aug;49(7):671-80. doi: 10.3109/15563650.2011.597034. Epub 2011 Aug 2.

DOI:10.3109/15563650.2011.597034
PMID:21809910
Abstract

INTRODUCTION

Human contact with potentially toxic plants, which may occur through abuse or by accident or attempted suicide, is frequent and sometimes results in clinically significant toxicity.

OBJECTIVE

The aim of the present study was to identify which plants may lead to severe poisoning, and to define the clinical relevance of plant toxicity for humans in Switzerland.

METHODS

We analyzed 42,193 cases of human plant exposure and 255 acute moderate, severe, and lethal poisonings, which were reported to the Swiss Toxicological Information Centre between January 1995 and December 2009.

RESULTS

Plant contact was rarely responsible for serious poisonings. Lethal intoxications were extremely rare and were caused by plants with cardiotoxic (Taxus baccata) or mitosis-inhibiting (Colchicum autumnale) properties.

CONCLUSIONS

Most often, plant contact was accidental and patients remained asymptomatic or developed mild symptoms, which fully resolved within a short time.

摘要

简介

人类接触潜在有毒植物的情况很常见,可能是由于滥用、意外或自杀企图导致的,有时会导致严重的临床毒性。

目的

本研究旨在确定哪些植物可能导致严重中毒,并确定瑞士人类植物毒性的临床相关性。

方法

我们分析了瑞士毒理学信息中心 1995 年 1 月至 2009 年 12 月期间报告的 42193 例人类植物暴露和 255 例急性中度、重度和致死性中毒病例。

结果

植物接触很少导致严重中毒。致死性中毒极为罕见,是由具有心脏毒性(欧洲红豆杉)或有丝分裂抑制作用的植物(秋水仙)引起的。

结论

大多数情况下,植物接触是意外的,患者无症状或出现轻度症状,短时间内完全缓解。

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