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[维生素B1、B6和B12与非甾体类抗风湿和镇痛药的相互作用:动物实验结果]

[The interactions of vitamins B1, B6 and B12 with non-steroidal antirheumatic and analgesic drugs: animal experiment results].

作者信息

Bartoszyk G D

机构信息

E. Merck, Biologische Forschung, Darmstadt.

出版信息

Klin Wochenschr. 1990 Jan 19;68(2):121-4. doi: 10.1007/BF01646859.

DOI:10.1007/BF01646859
PMID:2181201
Abstract

B-vitamins are therapeutically used in combination with nonsteroidal antiinflammatory drugs and weak analgesics. The animal experiments dealing with the antinociceptive and antiinflammatory activity of such combinations are reviewed with reference to the significance of the single vitamins B1, B6, and B12, the possible mechanisms of action, and the relevance of the animal data to man.

摘要

B族维生素在治疗上与非甾体抗炎药和弱镇痛药联合使用。本文参考单一维生素B1、B6和B12的重要性、可能的作用机制以及动物实验数据与人类的相关性,综述了有关此类联合用药的抗伤害感受和抗炎活性的动物实验。

相似文献

1
[The interactions of vitamins B1, B6 and B12 with non-steroidal antirheumatic and analgesic drugs: animal experiment results].[维生素B1、B6和B12与非甾体类抗风湿和镇痛药的相互作用:动物实验结果]
Klin Wochenschr. 1990 Jan 19;68(2):121-4. doi: 10.1007/BF01646859.
2
Do the B-vitamins exhibit antinociceptive efficacy in men? Results of a placebo-controlled repeated-measures double-blind study.B族维生素对男性是否具有抗伤害感受作用?一项安慰剂对照重复测量双盲研究的结果。
Neuropsychobiology. 1995;31(3):156-65. doi: 10.1159/000119186.
3
Antinociceptive properties of thiamine, pyridoxine and cyanocobalamin following repeated oral administration to mice.
Arzneimittelforschung. 1992 Feb;42(2):114-5.
4
Mechanisms of action of vitamin B1 (thiamine), B6 (pyridoxine), and B12 (cobalamin) in pain: a narrative review.维生素B1(硫胺素)、B6(吡哆醇)和B12(钴胺素)在疼痛中的作用机制:一项叙述性综述
Nutr Neurosci. 2023 Mar;26(3):235-253. doi: 10.1080/1028415X.2022.2034242. Epub 2022 Feb 14.
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[The importance of Vitamin B1, B6, B12 in the treatment of pain. New pharmacologic and clinical findings. Wiesbaden, 26 May 1989. Proceedings].[维生素B1、B6、B12在疼痛治疗中的重要性。新的药理学与临床研究结果。威斯巴登,1989年5月26日。会议论文集]
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Influence of vitamin B1, B6, and B12 on the control of fine motoric movements.维生素B1、B6和B12对精细运动控制的影响。
Bibl Nutr Dieta. 1986(38):104-9. doi: 10.1159/000412604.
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A contribution to the scientific assessment of degenerative and regenerative processes of peripheral nerve fibers following axonotmesis under the systemic administration of vitamins B1, B6 and B12--light and electron microscopy findings of the saphenous nerve in the rabbit.维生素B1、B6和B12全身给药后轴突切断术外周神经纤维退变与再生过程的科学评估——兔隐神经的光镜和电镜观察结果
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Synergistic interactions between the antinociceptive effect of Rhodiola rosea extract and B vitamins in the mouse formalin test.红景天提取物与维生素 B 族协同作用对小鼠福尔马林试验的镇痛效果。
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Studies on interactions of vitamin E with thiamine, niacin and vitamin B12.
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Vitamins as effectors of monensin production by Streptomyces cinnamonensis.维生素作为肉桂链霉菌产生莫能菌素的效应物。
Folia Microbiol (Praha). 1990;35(5):460-2. doi: 10.1007/BF02821417.

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Medicine (Baltimore). 2017 Apr;96(15):e6545. doi: 10.1097/MD.0000000000006545.

本文引用的文献

1
[On the pharmacology of vitamin B6 and its derivatives].[关于维生素B6及其衍生物的药理学]
Arzneimittelforschung. 1961 Oct;11:922-9.
2
Carrageenin-induced edema in hind paw of the rat as an assay for antiiflammatory drugs.角叉菜胶诱导大鼠后爪水肿作为抗炎药物的一种测定方法。
Proc Soc Exp Biol Med. 1962 Dec;111:544-7. doi: 10.3181/00379727-111-27849.
3
A comparison of the effects of vitamin B12 and aspirin in three experimental pain models in rats and mice.维生素B12与阿司匹林对大鼠和小鼠三种实验性疼痛模型影响的比较。
Psychopharmacology (Berl). 1983;81(3):228-31. doi: 10.1007/BF00427267.
4
Analgesic and anti-inflammatory properties of vitamins.维生素的镇痛和抗炎特性。
Int J Vitam Nutr Res Suppl. 1985;27:189-206.
5
A new and sensitive method for measuring thermal nociception in cutaneous hyperalgesia.一种用于测量皮肤痛觉过敏中热痛觉的新型灵敏方法。
Pain. 1988 Jan;32(1):77-88. doi: 10.1016/0304-3959(88)90026-7.
6
[Influence of enzyme inducers and inhibitors of the metabolism of xenobiotics and of the coenzyme forms of vitamins B1 and B2 on the anti-inflammatory effect of voltaren].
Farmakol Toksikol. 1988 Mar-Apr;51(2):69-71.
7
Behavioural and electrophysiological evidence for an analgesic effect of a non-steroidal anti-inflammatory agent, sodium diclofenac.非甾体抗炎药双氯芬酸钠镇痛作用的行为学和电生理学证据。
Pain. 1988 Dec;35(3):341-348. doi: 10.1016/0304-3959(88)90143-1.
8
B vitamins suppress spinal dorsal horn nociceptive neurons in the cat.B族维生素可抑制猫脊髓背角的伤害性神经元。
Neurosci Lett. 1988 Dec 19;95(1-3):192-7. doi: 10.1016/0304-3940(88)90655-6.
9
Pharmacology of diclofenac sodium.双氯芬酸钠的药理学
Am J Med. 1986 Apr 28;80(4B):34-8. doi: 10.1016/0002-9343(86)90077-x.
10
B-vitamins potentiate the antinociceptive effect of diclofenac in carrageenin-induced hyperalgesia in the rat tail pressure test.在大鼠尾压试验中,B族维生素可增强双氯芬酸对角叉菜胶诱导的痛觉过敏的抗伤害感受作用。
Neurosci Lett. 1989 Jun 5;101(1):95-100. doi: 10.1016/0304-3940(89)90447-3.