光疗期间和之后，经皮胆红素测定与血清胆红素值相当。
Covered skin transcutaneous bilirubin estimation is comparable with serum bilirubin during and after phototherapy.
机构信息
Department of Pediatrics, University of Texas Medical Branch, Galveston, TX 77555, USA.
出版信息
J Perinatol. 2012 Feb;32(2):129-31. doi: 10.1038/jp.2011.66. Epub 2011 Aug 4.
OBJECTIVE
To determine whether transcutaneous bilirubin (TcB) from covered skin (TcB-C) during and after discontinuing phototherapy (PHT) is reliable in treating neonatal jaundice.
STUDY DESIGN
In this prospective observational study, before starting PHT, part of the forehead was covered. TcB-C and TcB from exposed skin (TcB-E) to PHT were measured before starting PHT, on a 12-hourly basis while receiving PHT and 6 h after stopping PHT. We used ANOVA (analysis of variance) and Bonferroni's t-tests.
RESULT
A total of 39 infants were enrolled (mean gestation 39 weeks, 51% males and 80% Hispanic). The mean TSB over all time periods was 10.9±2.4, TcB-C 10.9±2.4 and TcB-E 7.2±3.4. Before PHT, there were no significant differences in bilirubin by all three techniques. TcB-C was not significantly different from TSB at any time point. However, TcB-E was significantly lower during PHT and after stopping PHT.
CONCLUSION
TcB-C is a reliable method in the management of neonatal jaundice.
目的
确定在停止光疗（PHT）期间和之后，从覆盖皮肤（TcB-C）获得的经皮胆红素（TcB）是否可用于治疗新生儿黄疸。
研究设计
在这项前瞻性观察研究中，在开始 PHT 之前，额部的一部分被覆盖。在开始 PHT 之前、接受 PHT 时每 12 小时以及停止 PHT 后 6 小时测量 TcB-C 和 PHT 时暴露皮肤（TcB-E）的 TcB。我们使用方差分析（ANOVA）和 Bonferroni t 检验。
结果
共纳入 39 名婴儿（平均胎龄 39 周，51%为男性，80%为西班牙裔）。所有时间段的平均 TSB 为 10.9±2.4，TcB-C 为 10.9±2.4，TcB-E 为 7.2±3.4。在开始 PHT 之前，三种技术的胆红素均无显著差异。在任何时间点，TcB-C 与 TSB 均无显著差异。然而，在 PHT 期间和停止 PHT 后，TcB-E 显著降低。
结论
TcB-C 是新生儿黄疸管理中的一种可靠方法。
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