Department of Medical Imaging, Jinan Military General Hospital, 25 Shifan Rd., Jinan, Shandong Province, China.
Eur Radiol. 2011 Dec;21(12):2597-603. doi: 10.1007/s00330-011-2218-z. Epub 2011 Aug 7.
To evaluate effects of vertebroplasty on restoration of vertebral body height and wedge angle and relief from pain in patients with osteoporotic compression fractures.
A retrospective study of 156 patients (232 levels) who had undergone vertebroplasty was conducted. Treated vertebrae with cleft included 49 patients (49 levels) and that without cleft 107 patients (183 levels). Effects on restoration of vertebral body height and wedge angle, and pain scores between pre- and post-procedure were statistically analyzed by using a paired-sample t test, and Kruskal Wallis test.
The height and wedge angle of the fractured vertebral body, and pain score, improved significantly after vertebroplasty. On a vertebra-by-vertebra analysis, the vertebral body height and wedge angle in the cleft group, were statistically significantly better post-procedure (P < 0.01); in the non-cleft group, there was nosignificant improved (P > 0.05). Pain relief was not statistically significant different between the two groups (P > 0.05).
Most patients experienced pain relief after vertebroplasty. After vertebroplasty, the height and wedge angle were significantly improved in the cleft group (p < 0.01), with no significant improvement in the non-cleft group (p > 0.05). Key Points • Vertebra with cleft is attributed to improvement of the spinal deformity • Vertebra without cleft was not associated with improvement of the spinal deformity • Vertebroplasty is an effective treatment strategy for osteoporotic compression fractures.
评估椎体成形术对骨质疏松性压缩性骨折患者椎体高度和楔角恢复及疼痛缓解的影响。
回顾性分析 156 例(232 个节段)接受椎体成形术治疗的患者。有裂隙的治疗椎体 49 例(49 个节段),无裂隙的 107 例(183 个节段)。采用配对样本 t 检验和 Kruskal Wallis 检验,对术前和术后椎体高度和楔角恢复及疼痛评分进行统计学分析。
骨折椎体的高度和楔角以及疼痛评分在椎体成形术后均显著改善。对逐个椎体进行分析,裂隙组术后椎体高度和楔角明显改善(P<0.01);无裂隙组无明显改善(P>0.05)。两组间疼痛缓解无统计学差异(P>0.05)。
大多数患者在椎体成形术后疼痛缓解。椎体成形术后,裂隙组脊柱畸形改善程度显著(P<0.01),无裂隙组无明显改善(P>0.05)。关键点:•有裂隙的椎体与脊柱畸形的改善有关•无裂隙的椎体与脊柱畸形的改善无关•椎体成形术是骨质疏松性压缩性骨折的有效治疗策略。