Sharma R K, Patki Pralhad S
Department of Dravyaguna and Rasashastra, Government Ayurvedic College, Guwahati, Assam, India.
J Ayurveda Integr Med. 2010 Jan;1(1):45-51. doi: 10.4103/0975-9476.59827.
Diabetes mellitus describes a metabolic disorder of multiple etiologies characterized by insulin resistance, relative insulin deficiency and hyperglycemia with disturbances of carbohydrate, fat and protein metabolism. The goal for treatment of diabetes is to prevent its acute manifestations and long-term microvascular and macrovascular complications. The present study was conducted to evaluate the efficacy and safety of an Ayurvedic formulation (GlucoCare Capsules) in non-insulin dependent diabetes mellitus. Fifty NIDDM patients of pitta-kapha prakriti attending the outpatient department of the Government Ayurvedic Medical College, Guwahati, Assam, India were included in the study, and randomly divided into 2 groups, GlucoCare and placebo. All received either GlucoCare or placebo in a dose of 2 capsules twice daily, before meals for 3 months. All 50 patients completed the study - no drop outs, withdrawals or patients lost to follow up. The GlucoCare group showed significant improvement in symptoms from the 2(nd) month till the end of the study. GlucoCare was well tolerated by all patients throughout the treatment period with no evidence of adverse effects. The study indicates clinical efficacy of GlucoCare Capsules in the management of NIDDM in those belonging to pitta-kapha prakriti. The formulation is well tolerated and appears safe in the dosage used.
糖尿病是一种由多种病因引起的代谢紊乱疾病，其特征为胰岛素抵抗、相对胰岛素缺乏以及碳水化合物、脂肪和蛋白质代谢紊乱导致的高血糖。糖尿病的治疗目标是预防其急性表现以及长期的微血管和大血管并发症。本研究旨在评估一种阿育吠陀制剂（葡糖康胶囊）治疗非胰岛素依赖型糖尿病的疗效和安全性。印度阿萨姆邦古瓦哈蒂政府阿育吠陀医学院门诊部的50名皮塔-卡法体质的非胰岛素依赖型糖尿病患者被纳入研究，并随机分为两组，即葡糖康组和安慰剂组。所有患者均每日两次、每次2粒胶囊，于饭前服用葡糖康或安慰剂，持续3个月。所有50名患者均完成了研究，无退出、脱落或失访情况。葡糖康组从第2个月直至研究结束症状均有显著改善。在整个治疗期间，所有患者对葡糖康耐受性良好，未出现不良反应。该研究表明，葡糖康胶囊对皮塔-卡法体质的非胰岛素依赖型糖尿病患者具有临床疗效。该制剂耐受性良好，在所使用的剂量下似乎是安全的。
