Dept. of Computer Science and Engineering, National Institute of Science and Technology, Berhampur, Orissa, India.
J Med Syst. 2012 Oct;36(5):2803-15. doi: 10.1007/s10916-011-9759-1. Epub 2011 Jul 21.
Depression is a common but worrying psychological disorder that adversely affects one's quality of life. It is more ominous to note that its incidence is increasing. On the other hand, screening and grading of depression is still a manual and time consuming process that might be biased. In addition, grades of depression are often determined in continuous ranges, e.g., 'mild to moderate' and 'moderate to severe' instead of making them more discrete as 'mild', 'moderate', and 'severe'. Grading as a continuous range is confusing to the doctors and thus affecting the management plan at large. Given this practical issue, the present paper attempts to differentiate depression grades more accurately using two neural net learning approaches-'supervised', i.e., classification with Back propagation neural network (BPNN) and Adaptive Network-based Fuzzy Inference System (ANFIS) classifiers, and 'unsupervised', i.e., 'clustering' technique with Self-organizing map (SOM), built in MATLAB 7. The reason for using the supervised and unsupervised learning approaches is that, supervised learning depends exclusively on domain knowledge. Supervision may induce biasness and subjectivities related to the decision-making. Finally, the performance of BPNN and ANFIS are compared and discussed. It was observed that ANFIS, being a hybrid system, performed much better compared to the BPNN classifier. On the other hand, SOM-based clustering technique is also found useful in constructing three distinct clusters. It also assists visualizing the multidimensional data clusters into 2-D.
抑郁症是一种常见但令人担忧的心理障碍,它会降低一个人的生活质量。更值得注意的是,抑郁症的发病率正在上升。另一方面,抑郁症的筛查和分级仍然是一个手动且耗时的过程,可能存在偏差。此外,抑郁症的严重程度通常以连续范围来确定,例如“轻度至中度”和“中度至重度”,而不是将其更离散地确定为“轻度”、“中度”和“重度”。以连续范围分级会使医生感到困惑,从而影响整体管理计划。鉴于这一实际问题,本文尝试使用两种神经网络学习方法(“监督式”,即使用反向传播神经网络(BPNN)和自适应网络模糊推理系统(ANFIS)分类器进行分类,以及“无监督式”,即使用 MATLAB 7 中的自组织映射(SOM)进行“聚类”技术,更准确地对抑郁症的严重程度进行区分。之所以使用监督式和无监督式学习方法,是因为监督式学习完全依赖于领域知识。监督可能会导致与决策相关的偏见和主观性。最后,对 BPNN 和 ANFIS 的性能进行了比较和讨论。结果表明,作为混合系统的 ANFIS 比 BPNN 分类器性能更好。另一方面,基于 SOM 的聚类技术也被发现对构建三个不同的聚类很有用。它还有助于将多维数据聚类可视化到 2-D。