小花龙血树枝干化学成分的细胞毒性。
Cytotoxicity of chemical constituents from the stems of Dalbergia parviflora.
机构信息
Natural Products Research Unit, Department of Chemistry and Center for Innovation in Chemistry, Faculty of Science, Khon Kaen University, Khon Kaen 40002, Thailand.
出版信息
Fitoterapia. 2011 Dec;82(8):1169-74. doi: 10.1016/j.fitote.2011.07.015. Epub 2011 Jul 30.
PMID:21835229
Abstract
Three new compounds, dalberpene, dalparvinene B and dalparvone B, as well as 12 known compounds were isolated from the heartwood of Dalbergia parviflora. Isoflavanone 13 showed strong cytotoxicity against KB, MCF-7 and NCI-H187 cell lines with IC₅₀ values ranging from 3.5 to 5.4μg/mL and it was inactive against normal cells.
摘要
从紫檀的心材中分离得到了 3 种新化合物（dalberpene、dalparvinene B 和 dalparvone B）以及 12 种已知化合物。异黄酮 13 对 KB、MCF-7 和 NCI-H187 细胞系表现出较强的细胞毒性，IC₅₀ 值范围为 3.5 至 5.4μg/mL，对正常细胞无活性。
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