Institut für Klinische Chemie/Zentrallaboratorien, Universitätsklinikum Eppendorf, Hamburg, Germany.
Clin Chem. 2011 Oct;57(10):1390-7. doi: 10.1373/clinchem.2011.167932. Epub 2011 Aug 11.
Pneumatic tube systems (PTSs) for the transport of blood samples are regaining popularity in medical centers after earlier reports that their use could introduce preanalytical distortions such as hemolysis and changes in blood gases.
We drew duplicate blood samples from 30 volunteers. One sample was hand transported, and the other sample was transported through a PTS together with a mini-data logger that provided continuous measurements of temperature, humidity, pressure, and acceleration. After transport the samples were analyzed at the same time. We looked for possible relationships of the transport method and the parameters measured by the data loggers with differences in hematological parameters, standard clinical chemistry analyses, blood coagulation, erythrocyte sedimentation rate, and blood gas analysis.
There were no significant differences in temperature, humidity, and pressure between the methods of transport, but we observed significant differences in 3-axis accelerations. The combined effect of these forces could be described by the right-tailed area under the vector sum acceleration distribution. Our data show that this area correlated with PTS speed and that PTS speed and the area under the curve exhibited a direct relation to the degree of hemolysis.
Assessment of 3-axis acceleration by use of data loggers can be used to identify preanalytical deviations that result from the transportation of blood samples in PTSs. Our approach could be used for the evaluation and regular control of PTSs without the need for repeated blood drawing and laboratory analyses.
在早些时候有报道称，使用气动输送系统（PTS）运输血样可能会导致溶血和血气变化等分析前偏差后，此类系统在医疗中心重新受到欢迎。
我们从 30 名志愿者中抽取了两份血样。一份手动运输，另一份与一个微型数据记录仪一起通过 PTS 运输，该数据记录仪可连续测量温度、湿度、压力和加速度。运输后，同时对这些样本进行分析。我们寻找了运输方法和数据记录仪测量的参数与血液学参数、标准临床化学分析、凝血、红细胞沉降率和血气分析差异之间的可能关系。
运输方法之间的温度、湿度和压力没有显著差异，但我们观察到三轴加速度有显著差异。这些力的综合作用可以用向量和加速度分布的右尾面积来描述。我们的数据表明，该面积与 PTS 速度相关，PTS 速度和曲线下面积与溶血程度呈直接关系。
使用数据记录仪评估三轴加速度可用于识别 PTS 运输过程中导致的分析前偏差。我们的方法可用于 PTS 的评估和定期控制，而无需重复采血和实验室分析。
