Ghannoum M A, Elteen K A, Ellabib M, Whittaker P A
Department of Botany and Microbiology, Kuwait University.
J Antimicrob Chemother. 1990 Feb;25(2):237-45. doi: 10.1093/jac/25.2.237.
The effects of octenidine and pirtenidine on yeasts (in particular Candida albicans) have been studied. MIC and MCC values have been established as well as the inhibitory effects on growth, budding and germ tube formation. The drugs were shown to cause extensive leakage of cytoplasmic contents from the cells which was correlated with morphological and ultrastructural changes in the yeast.
