Dhillon Steffi N, Deshpande Anshula N, Macwan Chirag, Patel Kinjal S, Shah Yash S, Jain Aishwarya A
Department of Pediatric and Preventive Dentistry, KM Shah Dental College and Hospital, Sumandeep Vidyapeeth, Vadodara, Gujarat, India.
Int J Clin Pediatr Dent. 2020;13(Suppl 1):S14-S25. doi: 10.5005/jp-journals-10005-1833.
The aim and objective of this study was to do a comparative evaluation of microhardness and enamel solubility (ES) of the treated surface enamel with resin infiltrant, fluoride varnish, and casein phosphopeptide-amorphous calcium phosphate (CPP-ACP).
An study was conducted on freshly extracted 85 sound permanent teeth of which 5 teeth were subjected to check for microhardness by the Vickers microhardness tester and the remaining teeth were exposed to demineralizing solution to create initial enamel lesions. These 80 teeth were assigned to four groups: group I-negative control ( = 20), group II-resin infiltrant ( = 20), group III-fluoride varnish ( = 20), and group IV-CPP-ACP ( = 20), and microhardness was checked after application. These teeth were exposed to caries attack three times a day for three consecutive days. The ES of these four groups was checked by calcium ion loss in the artificial cariogenic solution and whole saliva by an atomic absorption spectrophotometer.
It was found that none of the experimental groups reached the microhardness values of sound intact teeth. At 3rd day, the values of microhardness were: group II = group III > group IV > group I. Maximum ES was found for group I (control) followed with group IV.
All agents used in study remineralized initial carious lesion. Fluoride varnish has the highest microhardness and showed least ES compared to other remineralizing agents.
Fluoride varnish can be regarded as the choice of material to be used for the treatment of incipient carious lesions because of the low application frequency (once every 3-6 months), requires minimal patient compliance as it is a noninvasive procedure and less time consuming.
Dhillon SN, Deshpande AN, Macwan C, Comparative Evaluation of Microhardness and Enamel Solubility of Treated Surface Enamel with Resin Infiltrant, Fluoride Varnish, and Casein Phosphopeptide-amorphous Calcium Phosphate: An Study. Int J Clin Pediatr Dent 2020;13(S-1):S14-S25.
本研究的目的是对经树脂浸润剂、氟化物 varnish 和酪蛋白磷酸肽 - 无定形磷酸钙（CPP - ACP）处理的表面釉质的显微硬度和釉质溶解度（ES）进行比较评估。
对 85 颗新鲜拔除的健康恒牙进行研究，其中 5 颗牙齿用维氏显微硬度测试仪检测显微硬度，其余牙齿暴露于脱矿溶液中以形成初始釉质病变。这 80 颗牙齿分为四组：第一组为阴性对照组（n = 20），第二组为树脂浸润剂组（n = 20），第三组为氟化物 varnish 组（n = 20），第四组为 CPP - ACP 组（n = 20），应用后检测显微硬度。这些牙齿连续三天每天暴露于龋蚀攻击三次。通过原子吸收分光光度计检测人工致龋溶液和全唾液中钙离子流失情况来检查这四组的 ES。
发现所有实验组均未达到完好无损牙齿的显微硬度值。在第 3 天，显微硬度值为：第二组 = 第三组 > 第四组 > 第一组。第一组（对照组）的 ES 最大，其次是第四组。
研究中使用的所有药剂都使初始龋损再矿化。与其他再矿化剂相比，氟化物 varnish 的显微硬度最高，ES 最小。
由于应用频率低（每 3 - 6 个月一次），作为一种非侵入性操作且耗时少，患者依从性要求最低，氟化物 varnish 可被视为治疗早期龋损的首选材料。
Dhillon SN, Deshpande AN, Macwan C, 经树脂浸润剂、氟化物 varnish 和酪蛋白磷酸肽 - 无定形磷酸钙处理的表面釉质的显微硬度和釉质溶解度的比较评估：一项研究。《国际临床儿科牙科学杂志》2020；13（S - 1）：S14 - S25。
