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功能化磷酸三钙糊剂和酪蛋白磷酸肽-无定形磷酸钙对乳牙和恒牙釉质人工白斑病变再矿化潜力的评估

An Evaluation of Remineralization Potential of Functionalized Tricalcium Phosphate Paste and CPP-ACPF on Artificial White Spot Lesion in Primary and Permanent Enamel.

作者信息

Bhadoria Neha, Gunwal Mohit K, Kukreja Rinky, Maran Satish, Devendrappa Shashikiran N, Singla Shilpy

机构信息

Department of Pediatric Dentistry, Index Institute of Dental Sciences, Indore, Madhya Pradesh, India.

Department of Conservative Dentistry and Endodontics, VSPM's Dental College and Research Center, Maharashtra, Nagpur, India.

出版信息

Int J Clin Pediatr Dent. 2020 Nov-Dec;13(6):579-584. doi: 10.5005/jp-journals-10005-1813.

DOI:10.5005/jp-journals-10005-1813
PMID:33976478
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC8060932/
Abstract

AIM

Investigation and evaluation of remineralization potential of functionalized tricalcium phosphate paste (fTCP) and casein phosphopeptide-amorphous calcium phosphate (CPP-ACPF) paste on artificially created white spot lesion on human primary and permanent enamel through scanning electron microscopy and microhardness assessment.

MATERIALS AND METHODS

Sixty freshly extracted primary and permanent teeth were selected and artificial white spot lesion were created by using standardized demineralizing solution. Remineralization was carried out using the test pastes. The assessment of demineralization and remineralization was done through a scanning electron microscope and microhardness assessment.

RESULTS

Among the three groups, fTCP shows significantly higher increase in mean microhardness ( < 0.001) through ANOVA and the LSD test when compared to CPP-ACPF and control group. Also, the unpaired -test showed that mean change in microhardness in permanent teeth was significantly higher than primary teeth in different time intervals for both experimental groups. Surface morphology was assessed through a scanning electron microscope.

CONCLUSION

Based on the results of the current study, f-TCP showed comparatively more remineralization potential than CPP-ACP with fluoride.

HOW TO CITE THIS ARTICLE

Bhadoria N, Gunwal MK, Kukreja R, An Evaluation of Remineralization Potential of Functionalized Tricalcium Phosphate Paste and CPP-ACPF on Artificial White Spot Lesion in Primary and Permanent Enamel. Int J Clin Pediatr Dent 2020;13(6):579-584.

摘要

目的

通过扫描电子显微镜和显微硬度评估,研究和评价功能化磷酸三钙糊剂(fTCP)和酪蛋白磷酸肽 - 无定形磷酸钙(CPP - ACPF)糊剂对人工制造的人类乳牙和恒牙釉质白斑病变的再矿化潜力。

材料与方法

选取60颗新鲜拔除的乳牙和恒牙,使用标准化脱矿溶液制造人工白斑病变。使用测试糊剂进行再矿化。通过扫描电子显微镜和显微硬度评估来进行脱矿和再矿化的评估。

结果

在三组中,通过方差分析和LSD检验,与CPP - ACPF和对照组相比,fTCP显示出平均显微硬度显著更高的增加(<0.001)。此外,非配对t检验表明,在不同时间间隔内,两个实验组恒牙的显微硬度平均变化均显著高于乳牙。通过扫描电子显微镜评估表面形态。

结论

基于本研究结果,f - TCP显示出比含氟CPP - ACP相对更强的再矿化潜力。

如何引用本文

Bhadoria N, Gunwal MK, Kukreja R, 人工制造的乳牙和恒牙釉质白斑病变中功能化磷酸三钙糊剂和CPP - ACPF再矿化潜力的评估。《国际临床儿科牙科学杂志》2020;13(6):579 - 584。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/b467/8060932/6c7a1c6a2f88/ijcpd-13-579-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/b467/8060932/6c7a1c6a2f88/ijcpd-13-579-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/b467/8060932/6c7a1c6a2f88/ijcpd-13-579-g001.jpg

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