DNA damage response, genetic instability and cancer: from mechanistic insights to personalized treatment.
作者信息
Bartek Jiri
出版信息
Mol Oncol. 2011 Aug;5(4):303-7. doi: 10.1016/j.molonc.2011.07.006. Epub 2011 Jul 22.
Abstract
摘要
相似文献
1
DNA damage response, genetic instability and cancer: from mechanistic insights to personalized treatment.
Mol Oncol. 2011 Aug;5(4):303-7. doi: 10.1016/j.molonc.2011.07.006. Epub 2011 Jul 22.
2
Targeting DNA Repair.
Handb Exp Pharmacol. 2018;249:161-180. doi: 10.1007/164_2017_31.
3
[Microsatellite instability and cancer: from genomic instability to personalized medicine].
Med Sci (Paris). 2019 Jun-Jul;35(6-7):535-543. doi: 10.1051/medsci/2019093. Epub 2019 Jul 5.
4
Chromatin and genomic instability in cancer.
Int Rev Cell Mol Biol. 2021;364:ix-xvii. doi: 10.1016/S1937-6448(21)00116-7.
5
Endogenous DNA Damage as a Source of Genomic Instability in Cancer.
Cell. 2017 Feb 9;168(4):644-656. doi: 10.1016/j.cell.2017.01.002.
6
DNA repair defects and implications for immunotherapy.
J Clin Invest. 2018 Oct 1;128(10):4236-4242. doi: 10.1172/JCI122010.
7
Exploiting DNA repair defects for novel cancer therapies.
Mol Biol Cell. 2016 Jul 15;27(14):2145-8. doi: 10.1091/mbc.E15-10-0698.
8
DNA damage repair: historical perspectives, mechanistic pathways and clinical translation for targeted cancer therapy.
Signal Transduct Target Ther. 2021 Jul 9;6(1):254. doi: 10.1038/s41392-021-00648-7.
9
DNA replication and cancer: From dysfunctional replication origin activities to therapeutic opportunities.
Semin Cancer Biol. 2016 Jun;37-38:16-25. doi: 10.1016/j.semcancer.2016.01.001. Epub 2016 Jan 12.
10
Noncoding RNAs in DNA Damage Response: Opportunities for Cancer Therapeutics.
Methods Mol Biol. 2018;1699:3-21. doi: 10.1007/978-1-4939-7435-1_1.
引用本文的文献
1
Interplay of oxidative stress and antioxidant mechanisms in cancer development and progression.
Arch Toxicol. 2025 Sep 4. doi: 10.1007/s00204-025-04146-5.
2
Multi-Faceted Roles of ERCC1-XPF Nuclease in Processing Non-B DNA Structures.
DNA (Basel). 2022 Dec;2(4):231-247. doi: 10.3390/dna2040017. Epub 2022 Oct 11.
3
The class II myosin MYH4 safeguards genome integrity and suppresses tumor progression.
J Clin Invest. 2025 Jun 2;135(11). doi: 10.1172/JCI188165.
4
Dual Disruption of DNA Repair by a Novel CHK2 Inhibitor, ART-446, and Olaparib is a Promising Strategy for Triple-Negative Breast Cancer Therapy.
Biomol Ther (Seoul). 2025 May 1;33(3):458-469. doi: 10.4062/biomolther.2025.029. Epub 2025 Apr 8.
5
Spermine oxidase promotes Helicobacter pylori-mediated gastric carcinogenesis through acrolein production.
Oncogene. 2025 Feb;44(5):296-306. doi: 10.1038/s41388-024-03218-7. Epub 2024 Nov 10.
6
Genotoxic and Anti-Migratory Effects of Camptothecin Combined with Celastrol or Resveratrol in Metastatic and Stem-like Cells of Colon Cancer.
Cancers (Basel). 2024 Sep 26;16(19):3279. doi: 10.3390/cancers16193279.
7
Progerin mRNA expression in non-HGPS patients is correlated with widespread shifts in transcript isoforms.
NAR Genom Bioinform. 2024 Aug 29;6(3):lqae115. doi: 10.1093/nargab/lqae115. eCollection 2024 Sep.
8
Atherosclerosis Is a Smooth Muscle Cell-Driven Tumor-Like Disease.
Circulation. 2024 Jun 11;149(24):1885-1898. doi: 10.1161/CIRCULATIONAHA.123.067587. Epub 2024 Apr 30.
9
Prophage proteins alter long noncoding RNA and DNA of developing sperm to induce a paternal-effect lethality.
Science. 2024 Mar 8;383(6687):1111-1117. doi: 10.1126/science.adk9469. Epub 2024 Mar 7.
10
Microsatellite instability states serve as predictive biomarkers for tumors chemotherapy sensitivity.
iScience. 2023 Jun 7;26(7):107045. doi: 10.1016/j.isci.2023.107045. eCollection 2023 Jul 21.
本文引用的文献
1
p53: guardian of ploidy.
Mol Oncol. 2011 Aug;5(4):315-23. doi: 10.1016/j.molonc.2011.07.007. Epub 2011 Jul 30.
2
The underlying mechanism for the PARP and BRCA synthetic lethality: clearing up the misunderstandings.
Mol Oncol. 2011 Aug;5(4):387-93. doi: 10.1016/j.molonc.2011.07.001. Epub 2011 Jul 22.
3
Targeting ATR and Chk1 kinases for cancer treatment: a new model for new (and old) drugs.
Mol Oncol. 2011 Aug;5(4):368-73. doi: 10.1016/j.molonc.2011.07.002. Epub 2011 Jul 28.
4
Transcriptional modulation induced by ionizing radiation: p53 remains a central player.
Mol Oncol. 2011 Aug;5(4):336-48. doi: 10.1016/j.molonc.2011.06.004. Epub 2011 Jul 7.
5
Chromatin and the DNA damage response: the cancer connection.
Mol Oncol. 2011 Aug;5(4):349-67. doi: 10.1016/j.molonc.2011.06.001. Epub 2011 Jul 3.
6
Radioresistance of glioma stem cells: intrinsic characteristic or property of the 'microenvironment-stem cell unit'?
Mol Oncol. 2011 Aug;5(4):374-86. doi: 10.1016/j.molonc.2011.05.001. Epub 2011 May 20.
7
Centrosome clustering and chromosomal (in)stability: a matter of life and death.
Mol Oncol. 2011 Aug;5(4):324-35. doi: 10.1016/j.molonc.2011.05.003. Epub 2011 May 19.
8
Studies of genomic copy number changes in human cancers reveal signatures of DNA replication stress.
Mol Oncol. 2011 Aug;5(4):308-14. doi: 10.1016/j.molonc.2011.05.002. Epub 2011 May 20.
9
Genetic interactions in cancer progression and treatment.
Cell. 2011 Apr 1;145(1):30-8. doi: 10.1016/j.cell.2011.03.020.
10
Replication stress induces 53BP1-containing OPT domains in G1 cells.
J Cell Biol. 2011 Apr 4;193(1):97-108. doi: 10.1083/jcb.201011083. Epub 2011 Mar 28.
Zotero 插件