Mental Health Service, Rivierduinen, Leiden, The Netherlands.
Psychopathology. 2011;44(6):379-85. doi: 10.1159/000325169. Epub 2011 Aug 17.
This study examines the ability of the Scale of Prodromal Symptoms (SOPS) to differentiate between negative and depression symptoms in a young help-seeking ultrahigh risk (UHR) group.
SOPS data of 77 help-seeking patients at UHR for psychosis were analyzed with an exploratory factor analysis. The extracted Depression factor was validated with the Beck Depression Inventory (BDI). The extracted SOPS Negative symptoms factor was validated with the Negative symptoms subscale of the Positive and Negative Syndrome Scale (PANSS).
Four factors were extracted from the SOPS: a negative, depression, disorganized and positive factor. The Negative symptom factor consisted of three items (N1: social anhedonia and withdrawal, N3: decreased expression of emotion; N4: decreased experience of emotions and self), and could be validated with the PANSS Negative symptoms subscale. The Depression factor was also made up of three items (G2: dysphoric mood, G4: impaired tolerance to normal stress, and D4: personal hygiene/social attentiveness), and could be validated with the BDI.
Our results suggest that 3 items of the Negative symptoms subscale of the SOPS, 2 items of the General and 1 item of the Disorganization subscale differentiate validly between negative and depression symptoms in an UHR population.
本研究旨在检验前驱症状量表(SOPS)在区分年轻精神病高危(UHR)人群的阴性和抑郁症状方面的能力。
对 77 名寻求精神病帮助的 UHR 患者的 SOPS 数据进行了探索性因素分析。使用贝克抑郁量表(BDI)对提取的抑郁因子进行了验证。使用阳性和阴性症状量表(PANSS)的阴性症状子量表对提取的 SOPS 阴性症状因子进行了验证。
SOPS 中提取出四个因子:阴性、抑郁、紊乱和阳性因子。阴性症状因子由三个项目组成(N1:社交快感缺失和退缩,N3:表情减少,N4:减少情感体验和自我),可以与 PANSS 阴性症状子量表相验证。抑郁因子也由三个项目组成(G2:心境恶劣,G4:对正常压力的耐受性下降,D4:个人卫生/社交关注度),可以与 BDI 相验证。
我们的研究结果表明,SOPS 的阴性症状子量表中的 3 项、一般子量表中的 2 项和紊乱子量表中的 1 项可以有效地区分 UHR 人群中的阴性和抑郁症状。