Kalra Sanjay, Unnikrishnan Ambika Gopalakrishnan, Baruah Manash, Kalra Bharti
Department of Endocrinology, Bharti Hospital and BRIDE, Karnal, India.
Indian J Endocrinol Metab. 2011 Jul;15(Suppl 1):S12-6. doi: 10.4103/2230-8210.83056.
This paper reviews a novel insulin analogue, degludec, which has the potential to emerge as an ideal basal insulin. It reviews the limitations of existing basal insulin and analogues, and highlights the need for a newer molecule. The paper discusses the potential advantages of degludec, while reviewing its pharmacologic and clinical studies done so far. The paper assesses the potential role of insulin degludec and degludec plus in clinical diabetes practice.
本文综述了一种新型胰岛素类似物德谷胰岛素，它有可能成为一种理想的基础胰岛素。文中回顾了现有基础胰岛素及类似物的局限性，并强调了对更新型分子的需求。本文在回顾德谷胰岛素迄今为止的药理和临床研究时，讨论了其潜在优势。本文评估了德谷胰岛素及德谷胰岛素利拉鲁肽在临床糖尿病治疗中的潜在作用。
