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从 T-2 转化研究角度看改善骨折后骨质疏松症护理的干预措施。

A T-2 translational research perspective on interventions to improve post-fracture osteoporosis care.

机构信息

Department of Medicine, University of Alberta, 2F1.24 Walter Mackenzie Health Sciences Centre, University of Alberta Hospital, 8440-112th Street, Edmonton, Alberta, T6G 2B7, Canada.

出版信息

Osteoporos Int. 2011 Aug;22 Suppl 3:471-6. doi: 10.1007/s00198-011-1700-4. Epub 2011 Aug 17.

DOI:10.1007/s00198-011-1700-4
PMID:21847768
Abstract

The objectives of this paper are to: quickly outline the extent of the care gap in osteoporosis; define T-2 (knowledge) translation and its relationship to quality improvement; discuss the barriers to best practice in osteoporosis care after a fracture; convey the importance of rigor in design and evaluation of translational interventions by drawing upon examples from the broader literature; describe in some detail a series of post-fracture intervention trials conducted in Alberta, Canada; and make some conclusions specifically about osteoporosis interventions and more generally about T-2 translational research.

摘要

本文的目的是

快速概述骨质疏松症护理差距的程度;定义 T-2(知识)转化及其与质量改进的关系;讨论骨折后最佳骨质疏松症护理实践的障碍;通过借鉴更广泛文献中的例子,说明转化干预措施设计和评估的严谨性的重要性;详细描述在加拿大艾伯塔省进行的一系列骨折后干预试验;并专门针对骨质疏松症干预措施以及更普遍的 T-2 转化研究得出一些结论。

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本文引用的文献

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PLoS Med. 2011 Jan 18;8(1):e1000387. doi: 10.1371/journal.pmed.1000387.
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A systematic review of the effectiveness of interventions to improve post-fracture investigation and management of patients at risk of osteoporosis.一项系统评价干预措施改善骨折后骨质疏松风险患者调查和管理的效果。
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Osteoporos Int. 2011 Jun;22(6):1799-808. doi: 10.1007/s00198-010-1412-1. Epub 2010 Sep 29.
4
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Arthritis Rheum. 2009 Feb 15;61(2):209-15. doi: 10.1002/art.24097.
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