Department of Psychiatry, Western Psychiatric Institute and Clinic, University of Pittsburgh School of Medicine, Pittsburgh, PA 15213, USA.
Nicotine Tob Res. 2011 Dec;13(12):1321-5. doi: 10.1093/ntr/ntr114. Epub 2011 Aug 17.
Impulsivity is widely regarded as a risk factor for drug dependence. However, its relationship with the symptomatology of nicotine dependence is poorly understood.
To examine the nature of these relationships, we recruited 404 daily and occasional smokers from a predominantly student population and assessed the association between impulsivity, as measured by the Barratt Impulsiveness Scale (BIS-11) and several self-reported measures of smoking rate and nicotine dependence, including the Diagnostic and Statistical Manual's (DSM-IV) criteria.
Overall, impulsivity was high throughout the entire sample but only modestly associated with nicotine dependence. Within the diagnostic criteria of nicotine dependence, two symptoms, which reflect automatized or habitual smoking, were most strongly associated with impulsivity.
These data support recent human and animal work, which suggests that impulsivity is linked to the formation of habitual drug use, and are discussed within the framework of a dual-system account of drug seeking.
冲动性被广泛认为是药物依赖的一个风险因素。然而,它与尼古丁依赖症状的关系还不太清楚。
为了研究这些关系的本质,我们从一个主要由学生组成的人群中招募了 404 名每日吸烟者和偶尔吸烟者,并评估了冲动性(通过巴瑞特冲动量表(BIS-11)测量)与几种自我报告的吸烟率和尼古丁依赖测量指标之间的关系,包括《诊断与统计手册》(DSM-IV)的标准。
总的来说,整个样本中的冲动性都很高,但与尼古丁依赖的相关性仅适中。在尼古丁依赖的诊断标准中,反映自动化或习惯性吸烟的两个症状与冲动性的关联最强。
这些数据支持了最近的人类和动物研究,表明冲动性与习惯性药物使用的形成有关,并在药物寻求的双重系统理论框架内进行了讨论。