Department of Radiation Oncology, Beth Israel Medical Center, New York, New York, USA.
Head Neck. 2012 Jul;34(7):953-5. doi: 10.1002/hed.21843. Epub 2011 Aug 17.
Patients with small, low-/intermediate-risk parotid cancers, treated with surgery, and who have the single prognostic factor of close and/or positive margins, constitute an unusual subset. This study evaluates local control and morbidity associated with postoperative radiation therapy for low/intermediate grade parotid cancer in these patients.
Between 1999 and 2006, 17 patients underwent postoperative radiation therapy at Beth Israel Medical Center for acinic cell carcinoma or low-intermediate-grade mucoepidermoid carcinoma of the parotid with close/positive margins. Pathology, treatment, and follow-up data were retrospectively analyzed for morbidity and local control. Two- and 5-year estimates of survival outcomes were performed followed by an analysis of complications.
There were no local failures and no significant long-term complications.
Patients with small, low-risk cancer of the parotid gland have excellent local control and low treatment-related morbidity when receiving postoperative radiation therapy for positive or close margins of resection.
接受手术治疗、具有单一预后因素（切缘紧邻/阳性）的小且低/中风险腮腺癌患者构成了一类特殊亚群。本研究评估了术后放疗在这些患者中的局部控制和并发症发生率。
1999 年至 2006 年间，17 例接受术后放疗的患者患有腮腺的腺样囊性癌或低-中级别黏液表皮样癌，且切缘紧邻/阳性。对发病率和局部控制的病理学、治疗和随访数据进行了回顾性分析。进行了 2 年和 5 年生存结果的估计，然后对并发症进行了分析。
无局部失败，无明显长期并发症。
当腮腺小且低风险癌症患者因切除的切缘紧邻/阳性而接受术后放疗时，其局部控制效果极佳，且治疗相关的发病率较低。
