Department of Veterinary Surgery, Faculty of Veterinary Medicine, University of Kafkas, Kars,36100, Turkey.
Ir Vet J. 2005 Oct 1;58(10):567-70. doi: 10.1186/2046-0481-58-10-567.
: The aim of the present study was to investigate whether epidural administration of a xylazine-lidocaine combination accompanied by xylazine sedation would provide satisfactory analgesia for some surgical procedures on 10 calves admitted to the Department of Veterinary Surgery, University of Kafkas with perineal urolithiasis (n:2), rectovaginal fistula (n:1), atresia ani (n:2), omphalophlebitis (n:2), omphaloarteritis (n:1) and umbilical hernia (n:2).Following intramuscular injection of xylazine at a dose of 0.05 mg/kg for sedation, xylazine-lidocaine combination (0.2 mg/kg lidocaine + 0.02 mg/kg xylazine + 5 ml 0.9% NaCl) was administrated into the lumbosacral (L6-S1), sacrococcygeal (S5-Co1) or intercoccygeal (Co1-Co2) space. Heart rate, respiratory rate and rectal temperature were recorded prior to and during analgesia at 5, 10, 15, 30 and 60 minutes. Furthermore, depth and duration of analgesia were evaluated during surgical intervention.The study revealed that the combination of epidural xylazine-lidocaine with xylazine sedation was highly satisfactory for surgery of the lower urinary tract and the perineal region, but it was less so for surgery of the umbilical area.
: 本研究旨在探讨硬膜外给予二甲噻嗪-利多卡因合剂并辅以二甲噻嗪镇静是否能为因会阴尿道结石（n=2）、直肠阴道瘘（n=1）、肛门闭锁（n=2）、脐炎（n=2）、脐动脉炎（n=1）和脐疝（n=2）而入住兽医外科系的 10 头小牛的一些手术提供满意的镇痛。在进行镇静的 0.05 mg/kg 剂量的二甲噻嗪肌内注射后，将二甲噻嗪-利多卡因合剂（0.2 mg/kg 利多卡因+0.02 mg/kg 二甲噻嗪+5 ml 0.9% NaCl）注入腰荐（L6-S1）、荐尾（S5-Co1）或荐间（Co1-Co2）间隙。在镇痛前和镇痛后 5、10、15、30 和 60 分钟记录心率、呼吸频率和直肠温度。此外，在手术干预期间评估镇痛的深度和持续时间。研究表明，硬膜外二甲噻嗪-利多卡因与二甲噻嗪镇静联合使用对下尿路和会阴区域的手术非常满意，但对脐部区域的手术效果较差。
