Temple University School of Medicine, Philadelphia, Pennsylvania, United States of America.
PLoS One. 2011;6(8):e23224. doi: 10.1371/journal.pone.0023224. Epub 2011 Aug 11.
Prolonged wound-discharge following total hip arthroplasty (THA) is associated with an increased risk of infection. However, the potential role of hypertension in prolonging the duration of wound healing in this population has not yet been investigated. The aim of the present study was to compare healing in this population that has not yet been investigated. The aim of the present study was to compare hypertensive and normotensive THA patients in terms of the length of time required to achieve a dry wound and the length of stay in the hospital.
One hundred and twenty primary THA patients were evaluated. Pre-operative clinical history and physical examination revealed that 29 were hypertensive and 91 were normotensive. The two groups were statistically matched using optimal propensity score matching. The outcomes of interest were the number of days until a dry wound was observed and the duration of hospital stay.
The average systolic blood pressures were 150.1 mmHg and 120.3 mmHg for the hypertensive and normotensive groups, respectively. The mean number of days until the wound was dry was 3.79 for the hypertensive group and 2.03 for the normotensive group. Hypertensive patients required more days for their wounds to dry than normotensive patients (odds ratio = 1.65, p<0.05). No significant difference in the duration of hospital stay was found between the two groups.
Hypertensive patients had a higher risk of prolonged wound discharge after THA than their normotensive counterparts. Patients with prolonged wound drainage are at greater risk for infection. Clinicians should pay particular attention to infection-prevention strategies in hypertensive THA patients.
全髋关节置换术后(THA)长时间的伤口渗液与感染风险增加有关。然而,高血压在延长该人群伤口愈合时间方面的潜在作用尚未得到研究。本研究的目的是比较高血压和正常血压 THA 患者在达到伤口干燥所需的时间和住院时间方面的差异。
评估了 120 例初次 THA 患者。术前临床病史和体格检查显示,29 例为高血压,91 例为正常血压。使用最优倾向评分匹配对两组进行了统计学匹配。感兴趣的结果是观察到干燥伤口的天数和住院时间。
高血压组和正常血压组的平均收缩压分别为 150.1mmHg 和 120.3mmHg。高血压组伤口干燥的平均天数为 3.79 天,正常血压组为 2.03 天。高血压患者的伤口干燥时间长于正常血压患者(比值比=1.65,p<0.05)。两组的住院时间无显著差异。
高血压患者在 THA 后发生伤口渗液延长的风险高于正常血压患者。伤口引流时间延长的患者感染风险更高。临床医生应特别注意高血压 THA 患者的感染预防策略。