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飞秒激光晶状体治疗:小型猪晶状体白内障发生可能性的 1 年研究。

Femtosecond laser treatment of the crystalline lens: a 1-year study of possible cataractogenesis in minipigs.

机构信息

Institute of Applied Physics, Friedrich-Schiller-Universität Jena, Max-Wien-Platz 1, 07743, Jena, Germany.

出版信息

Graefes Arch Clin Exp Ophthalmol. 2011 Oct;249(10):1567-73. doi: 10.1007/s00417-011-1772-z. Epub 2011 Aug 19.

Abstract

BACKGROUND

To investigate the long-term stability and possible cataractogenesis after femtosecond laser treatment of the crystalline lens.

METHODS

The crystalline lenses of ten Göttingen minipigs® underwent femtosecond laser treatment. During a subsequent 1-year follow-up, the pigs were monitored by means of slit-lamp examination of the anterior segment and Scheimpflug imaging of the lens.

RESULTS

No laser-induced cataractogenesis was observed during the 1-year follow-up. The laser pattern showed a stable appearance under all examination devices.

CONCLUSION

Femtosecond laser treatment seems to be no trigger for cataract formation. Moreover, the long-term stability of the laser pattern makes it suitable for applications such as presbyopia treatment.

摘要

背景

研究飞秒激光晶状体治疗后的长期稳定性和可能的白内障发生情况。

方法

对 10 只哥廷根小型猪®的晶状体进行飞秒激光处理。在随后的 1 年随访期间,通过眼前节裂隙灯检查和晶状体的 Scheimpflug 成像对猪进行监测。

结果

在 1 年的随访期间,未观察到激光诱导的白内障发生。在所有检查设备下,激光模式均呈现稳定的外观。

结论

飞秒激光治疗似乎不是白内障形成的诱因。此外,激光模式的长期稳定性使其适用于治疗远视等应用。

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