Chapron Charles, Borghese Bruno, Streuli Isabelle, de Ziegler Dominique
Université Paris Descartes-Assistance Publique Hôpitaux de Paris, CHU Cochin, Department of Ob Gyn and Reproductive Medicine, Paris, France.
J Pediatr Adolesc Gynecol. 2011 Oct;24(5 Suppl):S7-12. doi: 10.1016/j.jpag.2011.07.006.
Endometriosis, a disease of young females that is possibly a devastating ailment requiring surgery, appears to be associated with certain features encountered in adolescence. First among these symptoms is the history of severe and lasting dysmenorrhea at the time of adolescence and the need to use oral contraceptives (OCs) for alleviating dysmenorrhea that failed to respond to nonsteroidal anti-inflammatory drugs (NSAIDs). Further awareness about existing associations between certain symptoms experienced at adolescence and the later development of endometriosis is important. Indeed, the possibility of diagnosing endometriosis earlier when suggested by clinical history could lead to less extensive surgery and thus, less damage. Experimental verification of this insight, however, is needed before the concept that early diagnosis means lesser destructive surgery can be ascertained.
子宫内膜异位症是一种年轻女性疾病，可能是一种需要手术治疗的严重疾病，似乎与青春期出现的某些特征有关。这些症状中首先是青春期时严重且持续的痛经病史，以及需要使用口服避孕药（OCs）来缓解对非甾体抗炎药（NSAIDs）无反应的痛经。进一步认识青春期出现的某些症状与子宫内膜异位症后期发展之间的现有关联很重要。事实上，根据临床病史提示更早诊断子宫内膜异位症的可能性可能会导致手术范围更小，从而损伤更小。然而，在确定早期诊断意味着破坏性较小的手术这一概念之前，需要对这一见解进行实验验证。
