NEIKER--Instituto Vasco de Investigación y Desarrollo Agrario, 48160 Derio, Bizkaia, Spain.
Appl Environ Microbiol. 2011 Oct;77(20):7405-7. doi: 10.1128/AEM.05530-11. Epub 2011 Aug 19.
Vaccination is considered one of the best options for controlling Coxiella burnetii infection in livestock. The efficacy of a phase I vaccine was investigated over 4 years in a sheep flock with confirmed C. burnetii infection. Shedding was not detected in ewes and yearlings in the last 2 years, but C. burnetii still persisted in the environment.
接种疫苗被认为是控制家畜感染贝氏柯克斯体的最佳选择之一。在一个有确诊感染贝氏柯克斯体的绵羊群中,经过 4 年的时间研究了 I 期疫苗的效果。在过去的 2 年中,母羊和一岁羔羊没有检测到脱落,但环境中仍存在贝氏柯克斯体。