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本文引用的文献

1
Modelling effectiveness of herd level vaccination against Q fever in dairy cattle.群体水平接种疫苗防控奶牛巴氏杆菌病效果的建模研究。
Vet Res. 2011 May 23;42(1):68. doi: 10.1186/1297-9716-42-68.
2
Reduction of Coxiella burnetii prevalence by vaccination of goats and sheep, The Netherlands.通过对山羊和绵羊进行疫苗接种来降低柯克斯体的流行率，荷兰。
Emerg Infect Dis. 2011 Mar;17(3):379-86. doi: 10.3201/eid1703.101157.
3
Coxiella burnetii shedding and environmental contamination at lambing in two highly naturally-infected dairy sheep flocks after vaccination.接种疫苗后，在两个高度自然感染的奶牛羊群分娩时，贝氏柯克斯体的脱落和环境污染。
Res Vet Sci. 2011 Dec;91(3):e58-63. doi: 10.1016/j.rvsc.2010.11.014. Epub 2010 Dec 17.
4
Q Fever.Q 热。
Vet Microbiol. 2010 Jan 27;140(3-4):297-309. doi: 10.1016/j.vetmic.2009.07.016. Epub 2009 Aug 8.
5
Efficiency of a phase 1 vaccine for the reduction of vaginal Coxiella burnetii shedding in a clinically affected goat herd.一种1期疫苗在减少临床感染山羊群中阴道贝氏柯克斯体脱落方面的效果。
Clin Microbiol Infect. 2009 Dec;15 Suppl 2:188-9. doi: 10.1111/j.1469-0691.2008.02220.x. Epub 2009 Sep 28.
6
Kinetics of Coxiella burnetii excretion in a commercial dairy sheep flock after treatment with oxytetracycline.土拉弗朗西斯菌感染羊驼后的排泄动力学研究。
Vet J. 2010 May;184(2):172-5. doi: 10.1016/j.tvjl.2009.01.017. Epub 2009 Mar 9.
7
Prevention of Coxiella burnetii shedding in infected dairy herds using a phase I C. burnetii inactivated vaccine.使用Ⅰ相伯纳特柯克斯体灭活疫苗预防感染奶牛群中伯纳特柯克斯体的排出。
Vaccine. 2008 Aug 12;26(34):4320-8. doi: 10.1016/j.vaccine.2008.06.023. Epub 2008 Jun 30.
8
Effect of vaccination with phase I and phase II Coxiella burnetii vaccines in pregnant goats.用I期和II期伯纳特柯克斯体疫苗对怀孕山羊进行疫苗接种的效果。
Vaccine. 2005 Aug 15;23(35):4392-402. doi: 10.1016/j.vaccine.2005.04.010.
9
Is Q fever an emerging or re-emerging zoonosis?Q热是一种新发还是再发的人畜共患病？
Vet Res. 2005 May-Jun;36(3):327-49. doi: 10.1051/vetres:2005010.
10
THE INFLUENCE OF PHASE ON THE PROTECTIVE POTENCY OF Q FEVER VACCINE.阶段对Q热疫苗保护效力的影响。
J Immunol. 1964 Mar;92:404-12.

对自然感染牛支原体的奶牛群进行疫苗接种以减少动物感染和环境污染的四年效果评估。

Four-year evaluation of the effect of vaccination against Coxiella burnetii on reduction of animal infection and environmental contamination in a naturally infected dairy sheep flock.

机构信息

NEIKER--Instituto Vasco de Investigación y Desarrollo Agrario, 48160 Derio, Bizkaia, Spain.

出版信息

Appl Environ Microbiol. 2011 Oct;77(20):7405-7. doi: 10.1128/AEM.05530-11. Epub 2011 Aug 19.

DOI:10.1128/AEM.05530-11
PMID:21856829
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC3194887/
Abstract

Vaccination is considered one of the best options for controlling Coxiella burnetii infection in livestock. The efficacy of a phase I vaccine was investigated over 4 years in a sheep flock with confirmed C. burnetii infection. Shedding was not detected in ewes and yearlings in the last 2 years, but C. burnetii still persisted in the environment.

摘要

接种疫苗被认为是控制家畜感染贝氏柯克斯体的最佳选择之一。在一个有确诊感染贝氏柯克斯体的绵羊群中，经过 4 年的时间研究了 I 期疫苗的效果。在过去的 2 年中，母羊和一岁羔羊没有检测到脱落，但环境中仍存在贝氏柯克斯体。