Laboratoire de Psychologie et Neuropsychologie Cognitives, FRE 3292 CNRS IUPDP Université Paris Descartes, Boulogne Billancourt, France.
PLoS One. 2011;6(8):e23125. doi: 10.1371/journal.pone.0023125. Epub 2011 Aug 9.
Early studies reported some abnormalities in saccade and vergence eye movements in children with vertigo and vergence deficiencies. The purpose of this study was to further examine saccade and vergence performance in a population of 44 children (mean age: 12.3±1.6 years) with vertigo symptoms and with different levels of vergence abnormalities, as assessed by static orthoptic examination (near point of convergence, prism bar and cover-uncover test).
Three groups were identified on the basis of the orthoptic tests: group 1 (n = 13) with vergence spasms and mildly perturbed orthoptic scores, group 2 (n = 14) with moderately perturbed orthoptic scores, and group 3 (n = 17) with severely perturbed orthoptic scores. Data were compared to those recorded from 28 healthy children of similar ages. Latency, accuracy and peak velocity of saccades and vergence movements were measured in two different conditions: gap (fixation offset 200 ms prior to target onset) and simultaneous paradigms. Binocular horizontal movements were recorded by a photoelectric device.
Group 2 of children with vergence abnormalities showed significantly longer latency than normal children in several types of eye movements recorded. For all three groups of children with vergence abnormalities, the gain was poor, particularly for vergence movement. The peak velocity values did not differ between the different groups of children examined.
Eye movement measures together with static orthoptic evaluation allowed us to better identify children with vergence abnormalities based on their slow initiation of eye movements. Overall, these findings support the hypothesis of a central deficit in the programming and triggering of saccades and vergence in these children.
早期研究报道眩晕和集合缺陷儿童的扫视和聚散眼动存在一些异常。本研究的目的是进一步检查 44 名（平均年龄：12.3±1.6 岁）有眩晕症状且集合异常程度不同的儿童的扫视和聚散运动功能，这些儿童通过静态斜视检查（集合近点、棱镜棒和遮盖-暴露试验）进行评估。
根据斜视检查结果将儿童分为三组：第 1 组（n=13）有集合痉挛和斜视检查结果轻度异常，第 2 组（n=14）有斜视检查结果中度异常，第 3 组（n=17）有斜视检查结果严重异常。将这些数据与 28 名年龄相近的健康儿童的记录数据进行比较。在两种不同条件下（注视偏移 200 毫秒前目标开始）测量扫视和聚散运动的潜伏期、准确性和峰值速度：间隙和同时范式。双眼水平运动通过光电装置记录。
在记录的几种眼动中，第 2 组有集合异常的儿童的潜伏期明显长于正常儿童。对于所有三组有集合异常的儿童，增益都很差，特别是对于集合运动。不同组间的峰值速度值没有差异。
眼动测量结果结合静态斜视评估可以更好地识别有集合异常的儿童，这些儿童的眼动起始较慢。总体而言，这些发现支持了在这些儿童中存在扫视和聚散运动的编程和触发中枢缺陷的假说。
