Department of Medicine, Baylor College of Medicine, Houston, Texas 77030, USA.
Semin Respir Crit Care Med. 2011 Aug;32(4):433-46. doi: 10.1055/s-0031-1283283. Epub 2011 Aug 19.
Rhinoviruses and coronaviruses cause significant morbidity in immunocompetent people of all ages and in patients with underlying chronic medical or immunosuppressed conditions. Newer diagnostic tests, such as polymerase chain reaction (PCR), have expanded our understanding of these respiratory viruses in clinical infections. These sensitive diagnostic tests have been used to describe new members of these virus families, such as human rhinovirus C (HRVC) and human coronavirus NL-63 (HCoV-NL63). The epidemiology of these newly described viruses will help us develop better intervention strategies.
鼻病毒和冠状病毒可导致各年龄段免疫功能正常人群以及患有潜在慢性医学疾病或免疫抑制人群发生严重疾病。聚合酶链反应（PCR）等新型诊断检测方法提高了我们对临床感染中这些呼吸道病毒的认识。这些灵敏的诊断检测方法已经用于描述这些病毒家族的新成员，例如人鼻病毒 C（HRVC）和人冠状病毒 NL-63（HCoV-NL63）。这些新描述病毒的流行病学情况将帮助我们制定更好的干预策略。
