Kurugöl Zafer, Midyat Levent, Türkoğlu Ebru, Ozacar Tijen
Department of Pediatrics, Ege University Faculty of Medicine, Izmir, Turkey.
Hum Vaccin. 2011 Sep;7(9):972-5. doi: 10.4161/hv.7.9.16370. Epub 2011 Sep 1.
In order to assess immunity to rubella in Izmir, Turkey, a total of 600 persons of 1-70 years of age were selected with cluster sampling. Of the 597 subjects, 120(20.1%) was susceptible to the rubella according to their serum antibody levels. Of children 1 to 6 years of age, 50.9% was found to be serologically susceptible to rubella. Rubella protection rates showed a age-related increase, reaching maximum in the 15-19 age group, in which 98.1% of these subjects had antibody titre above the full protective level. Of the 126 females in the reproductive age group, only 4(3.1%) were found to be serologically susceptible to rubella. Logistic regression analysis showed that among the several independent variables, only age (p< 0.001) was significantly associated with rubella protective antibody levels. Epidemiological studies should continue as the epidemiological characteristics of the disease may change depending on the uptake of MMR vaccination.
为评估土耳其伊兹密尔地区人群的风疹免疫力，采用整群抽样法共选取了600名年龄在1至70岁之间的人员。在这597名受试者中，根据血清抗体水平，有120人（20.1%）对风疹易感。在1至6岁的儿童中，发现50.9%的儿童血清学上对风疹易感。风疹保护率呈现出与年龄相关的增长趋势，在15至19岁年龄组达到最高，该年龄组中98.1%的受试者抗体滴度高于完全保护水平。在126名育龄期女性中，仅发现4人（3.1%）血清学上对风疹易感。逻辑回归分析表明，在几个独立变量中，只有年龄（p<0.001）与风疹保护性抗体水平显著相关。由于疾病的流行病学特征可能会因麻疹、腮腺炎和风疹联合疫苗（MMR）接种率的变化而改变，因此流行病学研究应继续进行。
