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小脑肿瘤所致认知缺陷:来自 Luria 实验室的历史案例报告。

Cognitive deficits from a cerebellar tumour: a historical case report from Luria's Laboratory.

机构信息

Natbrainlab, Section of Brain Maturation, Department of Forensic and Neurodevelopmental Sciences, King's College London, Institute of Psychiatry, London, UK.

出版信息

Cortex. 2012 Jan;48(1):26-35. doi: 10.1016/j.cortex.2011.07.001. Epub 2011 Jul 28.

DOI:10.1016/j.cortex.2011.07.001
PMID:21864837
Abstract

In 1964 an original case report from A.R. Luria's Laboratory of Neuropsychology was published in Cortex, being one of the first to draw a link between cerebellum and cognition, by highlighting the manifestation of 'pseudo-frontal' symptoms resulting from a cerebellar tumour. The findings of Luria and his team seem more consistent with modern views about cerebellar interactions with the frontal lobe and its contributions to behaviour than the views prevalent at the time of publication. The paper was originally submitted in Russian, and translated into Italian for its publication by Cortex. However, Cortex did not preserve the original manuscript in Russian. With the passage of time, and available only to the Italian readership, this case report inevitably fell into obscurity. Hence, we present a translation in English based on the published Italian version of the manuscript and discuss it in the context of Luria's general thinking about information processing in the brain and our current understanding of cortico-cerebellar system. The publication of this article gives readers an opportunity to consider the substantial influence of Soviet neuropsychology on the field internationally under Luria's leadership in the 1960s. It also shows that time is the best judge of ones scientific endeavours, and what may seem implausible today might prove to be valid and worthy of exploration tomorrow.

摘要

1964 年,A.R. 卢里亚神经心理学实验室的一篇原始病例报告发表在《大脑皮层》上,这是最早将小脑与认知联系起来的报告之一,报告强调了由小脑肿瘤引起的“假性额叶”症状的表现。卢里亚及其团队的发现似乎比当时发表的观点更符合现代关于小脑与额叶相互作用及其对行为贡献的观点。该论文最初用俄语提交,并由《大脑皮层》翻译成意大利语出版。然而,《大脑皮层》并没有保留俄语的原始手稿。随着时间的推移,由于只有意大利读者可以看到这篇论文,这个病例报告不可避免地变得鲜为人知。因此,我们根据发表的意大利语版本的手稿提供了一个英文翻译,并结合卢里亚关于大脑信息处理的一般思想以及我们当前对大脑皮层-小脑系统的理解对其进行了讨论。这篇文章的发表使读者有机会考虑到在卢里亚的领导下,20 世纪 60 年代苏联神经心理学在国际上的重要影响。它还表明,时间是对一个人科学努力的最好评判,今天看似难以置信的事情,明天可能会被证明是有效的,值得探索的。

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Cortex. 2012 Jan;48(1):26-35. doi: 10.1016/j.cortex.2011.07.001. Epub 2011 Jul 28.
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