Immunopharmacology, Departamento de Bioquímica e Imunologia, Instituto de Ciências Biológicas, Universidade Federal de Minas Gerais, Av. Antonio Carlos, 6627 - Pampulha, 31270-901 Belo Horizonte, MG, Brazil.
Microbes Infect. 2011 Dec;13(14-15):1121-32. doi: 10.1016/j.micinf.2011.07.012. Epub 2011 Aug 10.
We are not alone. The indigenous microbiota colonizes exposed surfaces and aids their hosts in several physiological activities. The transition between a non-colonized to a colonized state is associated with modification on the pattern of host inflammatory responsiveness. Therefore, innate immunity adapts to the colonized state of the host, suggesting that there is an acquired component in innate immune responses.
我们并非孑然一身。固有微生物组定植于暴露表面，并辅助宿主完成多种生理活动。从非定植状态向定植状态的转变与宿主炎症反应模式的改变有关。因此，固有免疫适应宿主的定植状态，这表明固有免疫反应中存在获得性成分。
