Department of Pediatrics, Rothman Center for Neuropsychiatry, University of South Florida College of Medicine, Saint Petersburg, FL 33701, USA.
Compr Psychiatry. 2012 Jul;53(5):525-34. doi: 10.1016/j.comppsych.2011.07.004. Epub 2011 Aug 24.
There are little data concerning clinical characteristics of women with Tourette disorder and chronic tic disorders in the extant literature and what is available mostly focuses on treatment-seeking individuals. The present research was conducted to provide a phenomenological characterization of tic disorders among 185 adult women with tic disorders. In addition to providing a descriptive overview of specific tic symptoms, tic severity, self-reported history of other psychiatric conditions, and impairment/lifestyle impact due to tics, this study compares 185 women and 275 men between 18 and 79 years old with tic disorders (who completed an identical battery of measures) based on demographic, social/economic status indicators, psychiatric variables (comorbidity, family psychiatric history, symptom presentation), adaptive functioning/quality of life, and impairment variables among a nonclinical adult sample. Finally, this research examines the relationship between tic severity and impairment indicators among women with tics. Sixty-eight percent of women in our sample reported severe motor tics and 40% reported severe phonic tics. Our exploratory data suggest that a sizeable number of adult women with persistent tics are suffering from psychiatric comorbidity and psychosocial consequences such as underachievement and social distress. Tic severity in women may be associated with lifestyle interference as well as with symptoms of depression and anxiety, and such symptoms may be more common among women with tics than in men with tics.
关于特发性运动障碍和慢性抽动障碍女性患者的临床特征,现有文献中的数据很少,并且现有的数据主要集中在寻求治疗的个体上。本研究旨在对 185 名成年抽动障碍女性患者的抽动障碍进行现象学特征描述。除了提供特定抽动症状、抽动严重程度、自我报告的其他精神疾病史以及抽动引起的损伤/生活方式影响的描述性概述外,本研究还比较了 185 名年龄在 18 至 79 岁之间的女性和 275 名患有抽动障碍的男性(他们完成了相同的一整套评估措施),这些参与者来自一个非临床成年样本,比较的依据是人口统计学、社会/经济地位指标、精神科变量(共病、家庭精神病史、症状表现)、适应功能/生活质量以及损伤变量。最后,本研究还检查了女性抽动严重程度与损伤指标之间的关系。我们样本中 68%的女性报告存在严重的运动性抽动,40%的女性报告存在严重的发音性抽动。我们的探索性数据表明,相当数量的患有持续性抽动的成年女性患有精神共病和心理社会后果,例如成绩不佳和社交困扰。女性的抽动严重程度可能与生活方式干扰以及抑郁和焦虑症状有关,并且这些症状在患有抽动的女性中比在患有抽动的男性中更为常见。