Institute of General and Inorganic Chemistry, Bulgarian Academy of Sciences, Acad. G. Bontchev Str., Bl.11, 1113, Sofia, Bulgaria.
J Mater Sci Mater Med. 2011 Oct;22(10):2187-96. doi: 10.1007/s10856-011-4415-3. Epub 2011 Aug 26.
Powders of magnesium-modified as well as zinc-modified calcium phosphates (Me-β-TCP and HA) with a (Ca(2+)+Mg(2+)+Zn(2+)+Na(+)+K(+))/P ratio of 1.3-1.4 and various Me(2+)/(Me(2+)+Ca(2+)) ratios (from 0.005 to 0.16) were prepared in biomimetic electrolyte systems at pH 8, mother liquid maturation and further syntering at 600-1000°C. Some differences in zinc and magnesium modifications have been prognosed on the basis of thermodynamic modeling of the studied systems and explained by the Mg(2+) and Zn(2+) ion chemical behaviour. The temperature as well as the degree of Zn(2+) and Mg(2+) ions substitutions were found to stabilize the β-TCP structure and this effect was more prononced for zinc. Thus, zinc-modified β-TCP powders consisting of idiomorphic crystals were obtained through sintering of Zn(2+) ion substituted calcium phosphates precursors at 800-1000°C. The Mg(2+) ion substitution leads to obtaining magnesium-modified β-TCP with spherical grains.
在 pH 值为 8 的仿生电解质体系中，通过母液成熟和进一步在 600-1000°C 下煅烧，制备了（Ca(2+)+Mg(2+)+Zn(2+)+Na(+)+K(+))/P 比为 1.3-1.4 且具有各种 Me(2+)/(Me(2+)+Ca(2+)) 比（从 0.005 到 0.16）的镁改性和锌改性的磷酸钙（Me-β-TCP 和 HA）粉末。根据所研究体系的热力学模型，对锌和镁改性的一些差异进行了预测，并通过 Mg(2+)和 Zn(2+)离子的化学行为进行了解释。发现温度以及 Zn(2+)和 Mg(2+)离子取代度能够稳定 β-TCP 结构，锌的这种效应更为明显。因此，通过在 800-1000°C 下烧结 Zn(2+)离子取代的磷酸钙前体，获得了由等轴晶体组成的锌改性β-TCP 粉末。Mg(2+)离子取代导致获得具有球形颗粒的镁改性β-TCP。
