Johnson & Johnson Ocular Surface and Visual Optics Department, Keio University School of Medicine, Tokyo, Japan.
Am J Ophthalmol. 2011 Dec;152(6):933-940.e2. doi: 10.1016/j.ajo.2011.05.025. Epub 2011 Aug 25.
To evaluate the effect of contact lens (CL) wear and visual display terminal (VDT) work on the ocular surface and tear functions.
Prospective case-control study.
Sixty-nine CL wearers (45 women and 24 men; mean age, 35.2 ± 7.3 years), and 102 age- and sex-matched non-CL wearers were enrolled in the study (66 women and 36 men; mean age, 36.7 ± 7.3 years). Ocular surface and tear function tests, including vital stainings (fluorescein and rose bengal), Schirmer test, tear meniscus height measurement, and tear film break-up time were performed. The subjective symptoms of dry eyes were evaluated using a dry eye symptom questionnaire. The participants were divided into 4 subgroups according to the total time of VDT work in 1 day (VDT work time in 1 day ≥ 4 hours or < 4 hours) and presence of CL wear. Main outcome measures included ocular surface vital staining scores, Schirmer test results, tear film break-up time, tear meniscus height measurement, and symptom questionnaire score.
CL users and long-term VDT workers showed significantly worse tear meniscus height values than non-CL users and short-term VDT workers (P < .001). The mean visual symptom scores in CL wearers and long-term VDT workers were significantly higher than the other groups (P < .001).
Office workers who wore CLs and spent more than 4 hours engaged in VDT work had a lower tear meniscus volume with significant dry eye and visual symptoms triggered by environmental factors.
评估隐形眼镜(CL)佩戴和视屏显示终端(VDT)工作对眼表面和泪液功能的影响。
前瞻性病例对照研究。
共纳入 69 名 CL 佩戴者(45 名女性,24 名男性;平均年龄 35.2 ± 7.3 岁)和 102 名年龄和性别匹配的非 CL 佩戴者(66 名女性,36 名男性;平均年龄 36.7 ± 7.3 岁)。进行眼表面和泪液功能测试,包括荧光素和孟加拉红染色的活体染色、泪液分泌试验、泪膜破裂时间、泪膜高度测量和 Schirmer 试验。采用干眼症状问卷评估干眼的主观症状。根据每天视屏显示终端工作的总时长(每天视屏显示终端工作时间≥4 小时或<4 小时)和是否佩戴隐形眼镜,将参与者分为 4 个亚组。主要观察指标包括眼表面活体染色评分、Schirmer 试验结果、泪膜破裂时间、泪膜高度测量和症状问卷评分。
CL 使用者和长期 VDT 工作者的泪膜高度值明显低于非 CL 使用者和短期 VDT 工作者(P<0.001)。CL 使用者和长期 VDT 工作者的平均视觉症状评分明显高于其他组(P<0.001)。
每天佩戴 CL 并从事 4 小时以上 VDT 工作的办公室工作人员泪膜高度值较低,且容易因环境因素而出现明显的干眼和视觉症状。