Department of Cardiology, Erciyes University School of Medicine, Kayseri, Turkey.
Clin Appl Thromb Hemost. 2012 Mar-Apr;18(2):211-4. doi: 10.1177/1076029611418964. Epub 2011 Aug 25.
Coronary artery ectasia (CAE) is characterized by an abnormal dilatation of the coronary arteries. Red cell distribution width (RDW) is a measure of heterogeneity in the size of red blood cell. In this study, we aimed to investigate RDW levels in patients with CAE.
The study population included 54 patients with CAE (28 males; mean age, 59 ± 12) and 40 individuals comprising the control group who had normal coronary arteries (17 males; mean age, 56 ± 10). Admission RDW was measured as part of the automated complete blood count.
The RDW was significantly higher in the CAE group than the control (P < .001). Also, high-sensitive C-reactive protein (hs-CRP) levels in patients with CAE were significantly higher as compared with controls (P < .001).
This study demonstrates that RDW and hs-CRP were higher in the CAE group compared with the control group. These results show that RDW is a reliable, simple, and inexpensive marker for patients with CAE.
冠状动脉扩张症(CAE)的特征是冠状动脉异常扩张。红细胞分布宽度(RDW)是衡量红细胞大小异质性的指标。本研究旨在探讨 CAE 患者的 RDW 水平。
研究人群包括 54 例 CAE 患者(28 名男性;平均年龄 59 ± 12)和 40 名正常冠状动脉的对照组个体(17 名男性;平均年龄 56 ± 10)。入院时通过自动化全血细胞计数测量 RDW。
CAE 组的 RDW 明显高于对照组(P <.001)。此外,与对照组相比,CAE 患者的高敏 C 反应蛋白(hs-CRP)水平也明显升高(P <.001)。
本研究表明,与对照组相比,CAE 组的 RDW 和 hs-CRP 更高。这些结果表明,RDW 是 CAE 患者可靠、简单、廉价的标志物。