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医疗无效:其含义及伦理意义。

Medical futility: its meaning and ethical implications.

作者信息

Schneiderman L J, Jecker N S, Jonsen A R

机构信息

School of Medicine, University of California, San Diego, La Jolla.

出版信息

Ann Intern Med. 1990 Jun 15;112(12):949-54. doi: 10.7326/0003-4819-112-12-949.

Abstract

The notion of medical futility has quantitative and qualitative roots that offer a practical approach to its definition and application. Applying these traditions to contemporary medical practice, we propose that when physicians conclude (either through personal experience, experiences shared with colleagues, or consideration of published empiric data) that in the last 100 cases a medical treatment has been useless, they should regard that treatment as futile. If a treatment merely preserves permanent unconsciousness or cannot end dependence on intensive medical care, the treatment should be considered futile. Unlike decision analysis, which defines the expected gain from a treatment by the joint product of probability of success and utility of outcome, our definition of futility treats probability and utility as independent thresholds. Futility should be distinguished from such concepts as theoretical impossibility, such expressions as "uncommon" or "rare," and emotional terms like "hopelessness." In judging futility, physicians must distinguish between an effect, which is limited to some part of the patient's body, and a benefit, which appreciably improves the person as a whole. Treatment that fails to provide the latter, whether or not it achieves the former, is "futile". Although exceptions and cautions should be borne in mind, we submit that physicians can judge a treatment to be futile and are entitled to withhold a procedure on this basis. In these cases, physicians should act in concert with other health care professionals, but need not obtain consent from patients or family members.

摘要

医疗无效的概念有其定量和定性的根源,这为其定义和应用提供了一种实用方法。将这些传统应用于当代医疗实践,我们建议,当医生得出结论(无论是通过个人经验、与同事分享的经验,还是对已发表的实证数据的考量),即在过去100例病例中某种医疗治疗毫无用处时,他们就应将该治疗视为无效。如果一种治疗仅仅维持永久无意识状态或无法终止对重症医疗护理的依赖,那么该治疗就应被视为无效。与通过成功概率和结果效用的联合乘积来定义治疗预期收益的决策分析不同,我们对无效的定义将概率和效用视为独立的阈值。无效应与理论上的不可能、诸如“不常见”或“罕见”之类的表述以及像“绝望”这样的情感性用语等概念区分开来。在判断无效时,医生必须区分局限于患者身体某些部位的效果和能显著改善患者整体状况的益处。未能提供后者的治疗,无论是否实现了前者,都是“无效的”。尽管应牢记例外情况和注意事项,但我们认为医生能够判断一种治疗是无效的,并有资格基于此拒绝进行某项操作。在这些情况下,医生应与其他医疗保健专业人员协同行动,但无需获得患者或家属的同意。

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