Liver Unit, Faculty of Medicine, Ziv Medical Center, Safed 13100, Israel.
World J Gastroenterol. 2011 Aug 7;17(29):3375-6. doi: 10.3748/wjg.v17.i29.3375.
Fatty liver is the most common liver disease worldwide. Patients with fatty liver disease die primarily from cardiovascular disease and not from chronic liver diseases. Hyperglycemia and hyperinsulinemia induce lipogenesis, thereby increasing the hepatic pool of fatty acids. This pool is also increased by increased delivery of fatty acids through the diet or lipolysis in adipose tissue. Nutritional consultations and lifestyle modification are important in the treatment of non-alcoholic fatty liver disease (NAFLD). Among the dietary constituents, combination of vitamin D, vitamin E, and omega-3 fatty acids shows promise for the treatment of NAFLD.
脂肪肝是世界范围内最常见的肝脏疾病。脂肪肝患者的主要死亡原因是心血管疾病，而不是慢性肝脏疾病。高血糖和高胰岛素血症可诱导脂肪生成，从而增加肝脏脂肪酸池。通过饮食或脂肪组织中的脂肪分解增加脂肪酸的输送也会增加该池。营养咨询和生活方式改变是非酒精性脂肪性肝病（NAFLD）的重要治疗方法。在饮食成分中，维生素 D、维生素 E 和 ω-3 脂肪酸的组合显示出治疗 NAFLD 的潜力。
