Agnamey P, Fortes-Lopes E, Raccurt C P, Boncy J, Totet A
CHU Amiens, Hôpital Sud, Service de Parasitologie et Mycologie Médicales, Avenue René Laënnec, Salouël, 80054 Amiens, France.
J Parasitol Res. 2012;2012:751951. doi: 10.1155/2012/751951. Epub 2011 Aug 25.
Fasciola hepatica, the aetiological agent of fascioliasis in the Caribbean region, occurs throughout the major islands of the Greater Antilles and in localised zones on two islands (Martinique and Saint Lucia) of the Lesser Antilles. However, apart from Puerto Rico, information regarding human fascioliasis in islands of the Caribbean is out of date or unavailable, or even nonexistent as in Haiti. The authors conducted a retrospective, cross-sectional serological survey in Port-au-Prince using a Western blotting test (LDBIO Diagnostics) on human fascioliasis in Haiti. A total of 216 serum samples obtained from apparently healthy adults were tested. The frequency of antibodies in serum samples of the study population was 6.5% (14/216). The immunodominant bands recognised in Western blots were 27-28 kDa (100%), 42 kDa (64%), 60 kDa, and 8-9 kDa (28%). This is the first survey to reveal a relatively low proportion of asymptomatic F. hepatica-infected humans in Haiti.
肝片吸虫是加勒比地区肝片吸虫病的病原体，在大安的列斯群岛的主要岛屿以及小安的列斯群岛的两个岛屿（马提尼克岛和圣卢西亚）的局部地区均有出现。然而，除波多黎各外，加勒比地区各岛屿关于人体肝片吸虫病的信息要么过时、要么无法获取，甚至在海地根本不存在此类信息。作者在太子港开展了一项回顾性横断面血清学调查，采用蛋白质印迹法（LDBIO诊断公司）检测海地人体肝片吸虫病情况。共检测了从看似健康的成年人中获取的216份血清样本。研究人群血清样本中的抗体阳性率为6.5%（14/216）。蛋白质印迹法中识别出的免疫显性条带为27 - 28 kDa（100%）、42 kDa（64%）、60 kDa和8 - 9 kDa（28%）。这是首次揭示海地无症状肝片吸虫感染人群比例相对较低的调查。
